Sound and Noise Sources in Sonotubometry: An Investigation of Eustachian Tube Assessment

Overview

Journal Ann Biomed Eng

Specialty Biomedical Engineering

Date 2024 May 13

PMID 38740729

Authors

Tobia Sebastiano Nava

Maximilian Nussbaumer

James R Tysome

Michael P F Sutcliffe

Affiliations

Soon will be listed here.

Abstract

This research aims to enhance the understanding of the acoustic processes occurring during sonotubometry, a method used to assess the Eustachian tube (ET) function. Recent advancements in digital signal processing enable a more comprehensive data analysis. In this project, a silicone model of the ET was developed to systematically study the existing noise and sound sources. These measurements were then compared with recordings from human subjects. Three distinct 'noise sources' were identified, which can influence the assessment of the ET opening using transmission measurements of the imposed signal: sound leakage from the speaker, a clicking noise at the initiation of ET opening, and rumbling/swallowing noise. Through spectral analysis, it was also possible to ascertain the spectral and temporal occurrence of these sound and noise types. The silicone model exhibited remarkable similarity to the healthy human ET, making it a robust experimental model for investigating the acoustics of sonotubometry. The findings underscore the significance of delving deeper into the analysed sound, as the noise occurring during sonotubometry can be easily misconstrued as an actual ET opening. Particularly, careful consideration is warranted when evaluating data involving clicking and swallowing noise.

References

Smith M, Takwoingi Y, Deeks J, Alper C, Bance M, Bhutta M . Eustachian tube dysfunction: A diagnostic accuracy study and proposed diagnostic pathway. PLoS One. 2018; 13(11):e0206946. PMC: 6224095. DOI: 10.1371/journal.pone.0206946. View

van der Avoort S, van Heerbeek N, Zielhuis G, Cremers C . Sonotubometry: eustachian tube ventilatory function test: a state-of-the-art review. Otol Neurotol. 2005; 26(3):538-43. DOI: 10.1097/01.mao.0000169765.00798.cd. View

PERLMAN H . Observations on the eustachian tube. AMA Arch Otolaryngol. 1951; 53(4):370-85. DOI: 10.1001/archotol.1951.03750040019002. View

Asenov D, Nath V, Telle A, Antweiler C, Walther L, Vary P . Sonotubometry with perfect sequences: First results in pathological ears. Acta Otolaryngol. 2010; 130(11):1242-8. DOI: 10.3109/00016489.2010.492481. View

Browning G, Gatehouse S . The prevalence of middle ear disease in the adult British population. Clin Otolaryngol Allied Sci. 1992; 17(4):317-21. DOI: 10.1111/j.1365-2273.1992.tb01004.x. View

Teixeira M, Banks J, Swarts J, Alper C, Doyle W . Eustachian tube opening measured by sonotubometry is poorer in adults with a history of past middle ear disease. Int J Pediatr Otorhinolaryngol. 2014; 78(4):593-8. PMC: 4017584. DOI: 10.1016/j.ijporl.2014.01.005. View

Liu Y, Johnson M, Matida E, Kherani S, Marsan J . Creation of a standardized geometry of the human nasal cavity. J Appl Physiol (1985). 2009; 106(3):784-95. DOI: 10.1152/japplphysiol.90376.2008. View

van der Avoort S, van Heerbeek N, F M Snik A, Zielhuis G, Cremers C . Reproducibility of sonotubometry as Eustachian tube ventilatory function test in healthy children. Int J Pediatr Otorhinolaryngol. 2006; 71(2):291-5. DOI: 10.1016/j.ijporl.2006.10.015. View

Beleskiene V, Lesinskas E, Januskiene V, Daunoraviciene K, Rauba D, Ivaska J . Eustachian Tube Opening Measurement by Sonotubometry Using Perfect Sequences for Healthy Adults. Clin Exp Otorhinolaryngol. 2016; 9(2):116-22. PMC: 4881315. DOI: 10.21053/ceo.2015.00626. View

10.

Amoako-Tuffour Y, Garland P, Bance M . Interpretation of sonotubometric data based on phase-shift detection. J Otolaryngol Head Neck Surg. 2016; 45(1):37. PMC: 4902982. DOI: 10.1186/s40463-016-0151-5. View

11.

Virtanen H . Sonotubometry. An acoustical method for objective measurement of auditory tubal opening. Acta Otolaryngol. 1978; 86(1-2):93-103. DOI: 10.3109/00016487809124724. View

12.

Nishino T . The swallowing reflex and its significance as an airway defensive reflex. Front Physiol. 2013; 3:489. PMC: 3539657. DOI: 10.3389/fphys.2012.00489. View

13.

Ehrt K, Fischer H, Dahl R, Punke C, Ovari A, Pau H . "Physiological" Ear Clicking: Its Origin and Potential Usability as a Test Tool for the Eustachian Tube Function. Otol Neurotol. 2016; 37(4):345-9. DOI: 10.1097/MAO.0000000000000973. View