Detection of Dopamine Based on Aptamer-Modified Graphene Microelectrode

Overview

Journal Sensors (Basel)

Publisher MDPI

Specialty Biotechnology

Date 2024 May 11

PMID 38733043

Authors

Cuicui Zhang

Tianyou Chen

Yiran Ying

Jing Wu

Affiliations

Soon will be listed here.

Abstract

In this paper, a novel aptamer-modified nitrogen-doped graphene microelectrode (Apt-Au-N-RGOF) was fabricated and used to specifically identify and detect dopamine (DA). During the synthetic process, gold nanoparticles were loaded onto the active sites of nitrogen-doped graphene fibers. Then, aptamers were modified on the microelectrode depending on Au-S bonds to prepare Apt-Au-N-RGOF. The prepared microelectrode can specifically identify DA, avoiding interference with other molecules and improving its selectivity. Compared with the N-RGOF microelectrode, the Apt-Au-N-RGOF microelectrode exhibited higher sensitivity, a lower detection limit (0.5 μM), and a wider linear range (1~100 μM) and could be applied in electrochemical analysis fields.

Citing Articles

Pd Nanoparticles Loaded on Cu Nanoplate Sensor for Ultrasensitive Detection of Dopamine.

Tan H, Zhang X, Xie J, Tang Z, Tang S, Xu L Sensors (Basel). 2024; 24(17).

PMID: 39275613 PMC: 11397903. DOI: 10.3390/s24175702.

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