Green Preparation and Antibacterial Activity Evaluation of AgNPs- Oil Nanoemulsion

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2024 May 11

PMID 38731501

Authors

Chunfang Ma

Bingnan Liu

Lingfeng Du

Wei Liu

Yue Zhu

Teng Chen

Zuhua Wang

Hongpeng Chen

Yuxin Pang

Affiliations

Soon will be listed here.

Abstract

Bacterial infection is a thorny problem, and it is of great significance to developing green and efficient biological antibacterial agents that can replace antibiotics. This study aimed to rapidly prepare a new type of green antibacterial nanoemulsion containing silver nanoparticles in one step by using oil (BBO) as an oil phase and tea saponin (TS) as a natural emulsifier and reducing agent. The optimum preparation conditions of the AgNPs@BBO-TS NE were determined, as well as its physicochemical properties and antibacterial activity in vitro being investigated. The results showed that the average particle size of the AgNPs@BBO-TS NE was 249.47 ± 6.23 nm, the PDI was 0.239 ± 0.003, and the zeta potential was -35.82 ± 4.26 mV. The produced AgNPs@BBO-TS NE showed good stability after centrifugation and 30-day storage. Moreover, the AgNPs@BBO-TS NE had an excellent antimicrobial effect on , , and . These results demonstrated that the AgNPs@BBO-TS NE produced in this study can be used as an efficient and green antibacterial agent in the biomedical field.

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