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Synthesis, Structure and Antibacterial Activity of Two Novel Coordination Polymers Based on ,'-bis(4-carbozvlbenzvl)-4-aminotoluene and Heterocyclic Ligand Against

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2024 May 11
PMID 38731481
Authors
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Abstract

As the use of antibiotics increases, the increasing resistance of bacteria is the main reason for the reduced efficiency of antibacterial drugs, making the research of new antibacterial materials become new hot spot. In this article, two novel coordination polymers (CPs), namely, [Cd(L)(bibp)] (1) and [Ni(L)(bib)] (2), where HL = ,'-bis(4-carbozvlbenzvl)-4-aminotoluene, bibp = 4,4'-bis(imidazol-1-yl)biphenyl, and bib = 1,3-bis(1-imidazoly)benzene, have been synthesized under solvothermal and hydrothermal condition. Structural clarification was performed through infrared spectrum and single-crystal X-ray diffraction analysis, while thermal analysis and XRD technology were used for the performance assessment of compounds and . In addition, antibacterial performance experiments showed that compounds and have certain selectivity in their antibacterial properties and have good antibacterial properties against . As the concentration of the compound increases, the inhibitory effect gradually strengthens, and when the concentration of the compound reaches 500 μg/mL and 400 μg/mL, the concentration of the solution no longer increases and has been completely inhibited.

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