» Articles » PMID: 3871158

Histiocytosis X: an Ophthalmological Review

Overview
Journal Br J Ophthalmol
Specialty Ophthalmology
Date 1985 Jan 1
PMID 3871158
Citations 18
Authors
Affiliations
Soon will be listed here.
Abstract

Of 76 children with histiocytosis X 18 had orbital involvement, and four developed additional neuro-ophthalmic complications. No instance of intraocular involvement was detected. Among those patients with ophthalmic involvement the main problems were bilateral or unilateral proptosis, ptosis, papilloedema, optic atrophy, and seventh nerve palsy. Only one patient developed a severe visual defect. Management of the ophthalmological complications depends not only on the extent of the orbital disease but also on the degree of systemic involvement. Overall management by a paediatric oncologist is mandatory.

Citing Articles

Clinicopathological study of ophthalmic cutaneous and mucocutaneous non-langerhans cell histiocytic lesions.

Alkatan H, Fatani D, Maktabi A, Alzahem T BMC Ophthalmol. 2024; 24(1):124.

PMID: 38504269 PMC: 10949701. DOI: 10.1186/s12886-024-03388-8.


Ophthalmic histiocytic lesions: a baseline demographic and clinicopathological study of 28 cases from two eye centers.

Alkatan H, Alzahem T, Maktabi A Int Ophthalmol. 2021; 42(4):1221-1232.

PMID: 34727265 DOI: 10.1007/s10792-021-02108-1.


Isolated intraocular histiocytosis-A rarely reported entity masquerading clinically as uveitis.

Moreker M, Dudani A, Sharma T, Patel K, Smruti B Indian J Ophthalmol. 2020; 68(9):2054-2056.

PMID: 32823479 PMC: 7690470. DOI: 10.4103/ijo.IJO_565_20.


Clinical spectrum and management outcomes of Langerhans cell histiocytosis of the orbit.

Koka K, Alam M, Subramanian N, Subramanian K, Biswas J, Mukherjee B Indian J Ophthalmol. 2020; 68(8):1604-1608.

PMID: 32709787 PMC: 7640849. DOI: 10.4103/ijo.IJO_1375_19.


MR imaging features of orbital Langerhans cell Histiocytosis.

Wu C, Li K, Hei Y, Lan P, Mu X BMC Ophthalmol. 2019; 19(1):263.

PMID: 31856763 PMC: 6923963. DOI: 10.1186/s12886-019-1269-9.


References
1.
Cohen M, Zornoza J, Cangir A, Murray J, Wallace S . Direct injection of methylprednisolone sodium succinate in the treatment of solitary eosinophilic granuloma of bone: a report of 9 cases. Radiology. 1980; 136(2):289-93. DOI: 10.1148/radiology.136.2.7403498. View

2.
Templeton A . Orbital tumours in African children. Br J Ophthalmol. 1971; 55(4):254-61. PMC: 1208279. DOI: 10.1136/bjo.55.4.254. View

3.
Anderson B, Margolis G, Lynn W . Ocular lesions related to disturbances in fat metabolism. Am J Ophthalmol. 1958; 45(4 Pt 2):23-41. DOI: 10.1016/0002-9394(58)90219-8. View

4.
Risdall R, Dehner L, Duray P, Kobrinsky N, Robison L, Nesbit Jr M . Histiocytosis X (Langerhans' cell histiocytosis). Prognostic role of histopathology. Arch Pathol Lab Med. 1983; 107(2):59-63. View

5.
Foucar E, Rosai J, DORFMAN R . The ophthalmologic manifestations of sinus histiocytosis with massive lymphadenopathy. Am J Ophthalmol. 1979; 87(3):354-67. DOI: 10.1016/0002-9394(79)90077-1. View