The Molecular Biological Mechanism of Hydrogen Therapy and Its Application in Spinal Cord Injury

Overview

Journal Drug Des Devel Ther

Specialty Pharmacology

Date 2024 May 6

PMID 38707612

Authors

Quan Hu

Yingxiao Li

Zhaochen Lin

Hao Zhang

Haoyue Chen

Cui Chao

Chuanliang Zhao

Affiliations

Soon will be listed here.

Abstract

Hydrogen, which is a novel biomedical molecule, is currently the subject of extensive research involving animal experiments and in vitro cell experiments, and it is gradually being applied in clinical settings. Hydrogen has been proven to possess anti-inflammatory, selective antioxidant, and antiapoptotic effects, thus exhibiting considerable protective effects in various diseases. In recent years, several studies have provided preliminary evidence for the protective effects of hydrogen on spinal cord injury (SCI). This paper provides a comprehensive review of the potential molecular biology mechanisms of hydrogen therapy and its application in treating SCI, with an aim to better explore the medical value of hydrogen and provide new avenues for the adjuvant treatment of SCI.

Citing Articles

Bibliometric analysis of the inflammation expression after spinal cord injury: current research status and emerging frontiers.

Li X, Jiao K, Liu C, Li X, Wang S, Tao Y Spinal Cord. 2024; 62(11):609-618.

PMID: 39363043 PMC: 11549042. DOI: 10.1038/s41393-024-01038-w.

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