Triglyceride-Glucose Index As A Biomarker Of Insulin Resistance, Diabetes Mellitus, Metabolic Syndrome, And Cardiovascular Disease: A Review
Overview
Authors
Affiliations
The triglyceride-glucose (TyG) index is one of the parameters that have been used in assessing insulin resistance. Triglycerides and fasting blood glucose are two low-cost, common laboratory indicators that are used to compute the TyG index. This article reviews the link between the TyG index and several aspects concerning insulin resistance-related disorders and cardiovascular disease, as well as the use of various TyG index cutoffs in the above conditions with sensitivity and specificity, respectively, in various populations in the world.
Dai M, Li D, Yu J, Liu Y, Zhang Q, Zhang W Sci Rep. 2025; 15(1):8571.
PMID: 40075094 PMC: 11903650. DOI: 10.1038/s41598-025-92779-y.
Abas A, Esawy M, Kamel F, Ali M Sci Rep. 2025; 15(1):6176.
PMID: 39979315 PMC: 11842543. DOI: 10.1038/s41598-024-82214-z.
Shan Y, Liu Q, Gao T BMC Endocr Disord. 2025; 25(1):25.
PMID: 39865224 PMC: 11765927. DOI: 10.1186/s12902-025-01848-w.
Xu H, Xie J, Xia Y, Niu H, Wang H, Zhan F Sci Rep. 2025; 15(1):2344.
PMID: 39833386 PMC: 11747252. DOI: 10.1038/s41598-025-86746-w.
The role of the triglyceride-glucose index as a biomarker of cardio-metabolic syndromes.
Gounden V, Devaraj S, Jialal I Lipids Health Dis. 2024; 23(1):416.
PMID: 39716258 PMC: 11664894. DOI: 10.1186/s12944-024-02412-6.