Effect of Water Temperature on the Anesthetic Effects of Alfaxalone in Carp (Cyprinus Carpio)

Overview

Journal J Adv Vet Anim Res

Specialty Veterinary Medicine

Date 2024 Apr 29

PMID 38680807

Authors

Kenichi Maeda

Daiki Hotta

Takuma Matsui

Satomi Iwai

Shozo Okanao

Affiliations

Soon will be listed here.

Abstract

Objective: To evaluate the effect of water temperature on intramuscular injected alfaxalone anesthesia in carp ().

Materials And Methods: Six healthy adult carp () were intramuscularly injected with alfaxalone (2.5, 5.0, or 7.5 mg/kg) at normal water temperature (25°C) and at low water temperature (2.5 mg/kg, 15°C). The respiratory rate, heart rate (HR), and anesthesia depth (AD) were evaluated every 5 min for 30 min after administration and every 1 h after 60 min after injection.

Results: The respiratory and HRs did not change significantly upon alfaxalone injection, regardless of dose. However, a dose-dependent increase in AD scores was observed. Furthermore, 2.5 mg/kg alfaxalone injected in 15°C water showed an almost equal anesthetic effect to that of 5.0 mg/kg alfaxalone in 25°C water.

Conclusion: Alfaxalone is readily available, and its anesthetic effect in carp was enhanced by lowering water temperature, illustrating the possibility of intramuscular injection of alfaxalone in fish.

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