Early-Onset Gastrointestinal Malignancies: An Investigation into a Rising Concern

Overview

Journal Cancers (Basel)

Publisher MDPI

Specialty Oncology

Date 2024 Apr 27

PMID 38672634

Authors

Aayush Vishwanath

Shreyas Krishna

Albert P Manudhane

Phil A Hart

Somashekar G Krishna

Affiliations

Soon will be listed here.

Abstract

There is growing recognition of early-onset gastrointestinal (GI) malignancies in young adults < 50 years of age. While much of the literature has emphasized colorectal cancer, these also include esophageal, gastric, liver, pancreatic, and biliary tract malignancies. Various factors, including lifestyle, hereditary, and environmental elements, have been proposed to explain the rising incidence of GI malignancies in the younger population. This review aims to provide an overview of the recent literature, including global trends and information regarding genetic and environmental risk factors.

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