The FKBP51s Splice Isoform Predicts Unfavorable Prognosis in Patients with Glioblastoma

Overview

Journal Cancer Res Commun

Specialty Oncology

Date 2024 Apr 23

PMID 38651817

Authors

Carolina Giordano

Laura Marrone

Simona Romano

Giuseppe Maria Della Pepa

Carlo Maria Donzelli

Martina Tufano

Mario Capasso

Vito Alessandro Lasorsa

Cristina Quintavalle

Giulia Guerri

Matia Martucci

Annamaria Auricchio

Marco Gessi

Evis Sala

Alessandro Olivi

Maria Fiammetta Romano

Simona Gaudino

Affiliations

Soon will be listed here.

Abstract

Significance: Our research suggests that by combining imaging with analysis of monocyte/macrophage subsets in patients with GBM, we can enhance our understanding of the disease and assist in its treatment. We discovered a similarity in the macrophage composition between the TME and PB, and through association with imaging, we could interpret macrophages. In addition, we identified a predictive biomarker that drew more attention to immune suppression of patients with GBM.

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