The Impact of Vitamin D on the Etiopathogenesis and the Progression of Type 1 and Type 2 Diabetes in Children and Adults

Overview

Journal Front Endocrinol (Lausanne)

Specialty Endocrinology

Date 2024 Apr 23

PMID 38650715

Authors

Candong Li

Jiaowen Fu

Yipeng Ye

Junsen Li

Yangli He

Tuanyu Fang

Affiliations

Soon will be listed here.

Abstract

Diabetes is a common chronic metabolic disease with complex causes and pathogenesis. As an immunomodulator, vitamin D has recently become a research hotspot in the occurrence and development of diabetes and its complications. Many studies have shown that vitamin D can reduce the occurrence of diabetes and delay the progression of diabetes complications, and vitamin D can reduce oxidative stress, inhibit iron apoptosis, promote Ca influx, promote insulin secretion, and reduce insulin resistance. Therefore, the prevention and correction of vitamin D deficiency is very necessary for diabetic patients, but further research is needed to confirm what serum levels of vitamin D are maintained in the body. This article provides a brief review of the relationship between vitamin D and diabetes, including its acute and chronic complications.

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