PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin

Overview

Journal Mol Imaging Biol

Publisher Springer

Specialties Molecular Biology
Radiology

Date 2024 Apr 22

PMID 38649626

Authors

Shayla Shmuel

Sebastien Monette

Dina Ibrahim

Patricia M R Pereira

Affiliations

Soon will be listed here.

Abstract

This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.

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