» Articles » PMID: 38646321

Chronic Visual Abnormality in an Elderly Patient With Temporal Lobe Epilepsy

Overview
Journal Cureus
Date 2024 Apr 22
PMID 38646321
Authors
Affiliations
Soon will be listed here.
Abstract

A 79-year-old woman visited our department for chronic visual field abnormalities with a floating sensation for two months. Neurological and ophthalmologic examinations yielded normal results, except for brain MRI indicating left hippocampal atrophy. Cognitive function tests were normal. EEG revealed frequent spikes and slow waves in the left frontotemporal region, corroborated by reduced accumulation in I-iomazenil single photon emission computed tomography. A diagnosis of temporal lobe epilepsy was established, and treatment with lacosamide resulted in a remarkable improvement in symptoms and EEG findings. Mild focal seizures from the temporal region might cause mild impaired awareness, resulting in the patient's report as a sensation of uncertainty between the self and the outside world, mimicking ophthalmologic abnormalities. The repeated nature of the seizures contributed to the absence of the term "transient" in symptom description. Diagnosing epilepsy in the elderly proves challenging due to nonspecific complaints.

References
1.
Dubey D, Alqallaf A, Hays R, Freeman M, Chen K, Ding K . Neurological Autoantibody Prevalence in Epilepsy of Unknown Etiology. JAMA Neurol. 2017; 74(4):397-402. DOI: 10.1001/jamaneurol.2016.5429. View

2.
Hauser W . Seizure disorders: the changes with age. Epilepsia. 1992; 33 Suppl 4:S6-14. DOI: 10.1111/j.1528-1157.1992.tb06222.x. View

3.
Blair R . Temporal lobe epilepsy semiology. Epilepsy Res Treat. 2012; 2012:751510. PMC: 3420439. DOI: 10.1155/2012/751510. View

4.
Tombini M, Assenza G, Ricci L, Lanzone J, Boscarino M, Vico C . Temporal Lobe Epilepsy and Alzheimer's Disease: From Preclinical to Clinical Evidence of a Strong Association. J Alzheimers Dis Rep. 2021; 5(1):243-261. PMC: 8150253. DOI: 10.3233/ADR-200286. View

5.
Levite M, Goldberg H . Autoimmune Epilepsy - Novel Multidisciplinary Analysis, Discoveries and Insights. Front Immunol. 2022; 12:762743. PMC: 8790247. DOI: 10.3389/fimmu.2021.762743. View