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Cognitive Rehabilitation in Bipolar Spectrum Disorder: A Systematic Review

Overview
Specialty Neurology
Date 2024 Apr 22
PMID 38645887
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Abstract

Background And Objectives: Neurocognitive deficits in bipolar disorder (BD) have a negative impact on the quality of life, even during the euthymic phase. And many studies conducted to improve cognitive deficits in bipolar disorder. This systematic review aims to summarize studies on cognitive rehabilitation (CR) conducted in bipolar patients and evaluate its impact on neurocognitive deficits. The primary objective is to explore how CR interventions can enhance cognitive functioning, treatment outcomes, and overall quality of life in this population.

Methods: A comprehensive search was conducted on PubMed, Google Scholar, Scopus, Embase, and PsycINFO databases from 1950 to 2023, following the 2015 PRISMA-P guidelines, using search terms related to BD and CR.

Results: The initial search yielded 371 titles across the five databases. After applying inclusion and exclusion criteria through screening, a total of 23 articles were included in the study. The selected articles evaluated verbal memory, attention, executive functions, and social cognition.

Conclusion: The findings suggest that CR can be an effective treatment approach for bipolar patients, aimed at enhancing their cognitive abilities, treatment outcomes, and overall quality of life. The primary finding of this study indicates that cognitive-behavioral therapy (CBT) protocols, skill training, and homework exercises, which offer a daily structure, social support, and opportunities for exchanging coping strategies, are more effective in enhancing cognitive functions. However, it is important to acknowledge the notable limitations of this review. Firstly, we did not assess the methodological rigor of the included studies. Additionally, there was a lack of detailed analysis regarding specific cognitive rehabilitation approaches that adhere to core CR principles, resulting in increased heterogeneity within the reviewed studies.

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References
1.
van den Berg K, Hendrickson A, Hales S, Voncken M, Keijsers G . Comparing the effectiveness of imagery focussed cognitive therapy to group psychoeducation for patients with bipolar disorder: A randomised trial. J Affect Disord. 2022; 320:691-700. DOI: 10.1016/j.jad.2022.09.160. View

2.
Martinez-Aran A, Vieta E, Torrent C, Sanchez-Moreno J, Goikolea J, Salamero M . Functional outcome in bipolar disorder: the role of clinical and cognitive factors. Bipolar Disord. 2007; 9(1-2):103-13. DOI: 10.1111/j.1399-5618.2007.00327.x. View

3.
Sanchez-Moreno J, Martinez-Aran A, Gadelrab H, Cabello M, Torrent C, Bonnin C . The role and impact of contextual factors on functioning in patients with bipolar disorder. Disabil Rehabil. 2010; 32 Suppl 1:S94-S104. DOI: 10.3109/09638288.2010.520810. View

4.
Sole B, Bonnin C, Mayoral M, Amann B, Torres I, Gonzalez-Pinto A . Functional remediation for patients with bipolar II disorder: improvement of functioning and subsyndromal symptoms. Eur Neuropsychopharmacol. 2014; 25(2):257-64. DOI: 10.1016/j.euroneuro.2014.05.010. View

5.
Gillissie E, Lui L, Ceban F, Miskowiak K, Gok S, Cao B . Deficits of social cognition in bipolar disorder: Systematic review and meta-analysis. Bipolar Disord. 2021; 24(2):137-148. DOI: 10.1111/bdi.13163. View