Metabolic Risks Remain a Serious Threat to Cardiovascular Disease: Findings from the Global Burden of Disease Study 2019

Overview

Journal Intern Emerg Med

Publisher Springer

Specialties Emergency Medicine
General Medicine

Date 2024 Apr 20

PMID 38642311

Authors

Runhong Li

Jinang Shao

Chengxiang Hu

Tong Xu

Jin Zhou

Jiaqi Zhang

Qitong Liu

Mengying Han

Ning Ning

Xiaoting Fan

Wenhui Zhou

Rong Huang

Yanan Ma

Lina Jin

Affiliations

Soon will be listed here.

Abstract

Metabolic factors are major and controllable risk factors for cardiovascular diseases (CVD), and few studies have described this burden. We aim to assess it from 1990 to 2019 and predict the trends through 2034. Global Burden of Disease (GBD) provides data on sex, age, and socio-demographic index (SDI) levels. Numbers, age-standardized death rates (ASDR) and estimated annual percentage change (EAPC) were used. Future trends were estimated by NORDPRED model. The deaths cases of metabolic-related CVD increased from 8.61 million (95% UI: 7.91-9.29) to 13.71 million (95% UI: 12.24-14.94) globally. The ASDR continued to decline globally (EAPC = -1.36). The burden was heavier in male and middle-aged people and elderly people. CVD-related ASDR caused by high systolic blood pressure (SBP) had a downward trend globally (EAPC = -1.45), while trends of high body mass index (BMI) (EAPC = 1.29, 1.97, 0.92) and fasting plasma glucose (FPG) (EAPC = 0.95, 1.08, 0.46) were increasing in the middle, low-middle, and low SDI regions, respectively. Compared to 2015-2019, cumulative deaths will increase by 27.85% from 2030 to 2034, while ASDR will decrease 10.47%. The metabolic-related CVD burden remained high globally and deaths will continue to rise in the future. Men, middle-aged and elderly people were focus of concern. High SBP was globally well-managed over the past 30 years, but the CVD burden due to high BMI and FPG remained high. Exceptional initiatives are needed to regarding interventions targeting high BMI and FPG in middle and lower SDI regions.

Citing Articles

Sociodemographic index-age differences in the global prevalence of cardiovascular diseases, 1990-2019: a population-based study.

Li X, Zhao C, Liu M, Zhao W, Pan H, Wang D Arch Public Health. 2025; 83(1):2.

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