Comprehensive Genome-Wide Natural Variation and Expression Analysis of Tubby-like Proteins Gene Family in

Overview

Journal Plants (Basel)

Date 2024 Apr 13

PMID 38611516

Authors

Sendi Mejia

Jose Lorenzo B Santos

Christos Noutsos

Affiliations

Soon will be listed here.

Abstract

The Tubby-like proteins (TLPs) gene family is a group of transcription factors found in both animals and plants. In this study, we identified twelve TLPs, divided into six groups based on conserved domains and evolutionary relationships. We predicted cis-regulatory elements involved in light, hormone, and biotic and abiotic stresses. The expression patterns in response to light and hormones revealed that , , , and are involved in light responses, and is involved in ABA responses. Furthermore, , , , and are expressed throughout vegetative and reproductive stages, whereas , , , and are expressed at germinating grains and early vegetative development, and , , , and are expressed at the early reproduction stage. The natural variation in the eleven most diverged lines revealed high conservation levels of BdTLP1-6 to high variation in BdTLP7-14 proteins. Based on diversifying selection, we identified amino acids in BdTLP1, 3, 8, and 13, potentially substantially affecting protein functions. This analysis provided valuable information for further functional studies to understand the regulation, pathways involved, and mechanism of BdTLPs.

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