Fluorocarbon Plasma-Polymerized Layer Increases the Release Time of Silver Ions and the Antibacterial Activity of Silver-Based Coatings

Overview

Journal Nanomaterials (Basel)

Date 2024 Apr 12

PMID 38607143

Authors

Linda Bonilla-Gameros

Pascale Chevallier

Xavier Delvaux

L Astrid Yanez-Hernandez

Laurent Houssiau

Xavier Minne

Vanessa P Houde

Andranik Sarkissian

Diego Mantovani

Affiliations

Soon will be listed here.

Abstract

Silver-based antibacterial coatings limit the spread of hospital-acquired infections. Indeed, the use of silver and silver oxide nanoparticles (Ag and AgO NPs) incorporated in amorphous hydrogenated carbon (a-C:H) as a matrix demonstrates a promising approach to reduce microbial contamination on environmental surfaces. However, its success as an antibacterial coating hinges on the control of Ag release. In this sense, if a continuous release is required, an additional barrier is needed to extend the release time of Ag. Thus, this research investigated the use of a plasma fluoropolymer (CF) as an additional top layer to elongate Ag release and increase the antibacterial activity due to its high hydrophobic nature. Herein, a porous CF film was deposited on a-C:H containing Ag and AgO NPs using pulsed afterglow low pressure plasma polymerization. The chemical composition, surface wettability and morphology, release profile, and antibacterial activity were analyzed. Overall, the combination of a-C:H:Ag (12.1 at. % of Ag) and CF film (120.0°, F/C = 0.8) successfully inactivated 88% of and delayed biofilm formation after 12 h. Thus, using a hybrid approach composed of Ag NPs and a hydrophobic polymeric layer, it was possible to increase the overall antibacterial activity of the coating.

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