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Chronological Vs Biological Age in Interventional Cardiology: A Comprehensive Approach to Care for Older Adults: JACC Family Series

Overview
Publisher Elsevier
Date 2024 Apr 10
PMID 38597844
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Abstract

Aging is the gradual decline in physical and physiological functioning leading to increased susceptibility to stressors and chronic illnesses, including cardiovascular disease. With an aging global population, in which 1 in 6 individuals will be older than 60 years by 2030, interventional cardiologists are increasingly involved in providing complex care for older individuals. Although procedural aspects remain their main clinical focus, interventionalists frequently encounter age-associated risks that influence eligibility for invasive care, decision making during the intervention, procedural adverse events, and long-term management decisions. The unprecedented growth in transcatheter interventions, especially for structural heart diseases at extremes of age, have pushed age-related risks and implications for cardiovascular care to the forefront. In this JACC state-of-the-art review, the authors provide a comprehensive overview of the aging process as it relates to cardiovascular interventions, with special emphasis on the difference between chronological and biological aging. The authors also address key considerations to improve health outcomes for older patients during and after their invasive cardiovascular care. The role of "gerotherapeutics" in interventional cardiology, technological innovation in measuring biological aging, and the integration of patient-centered outcomes in the older adult population are also discussed.

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References
1.
Otto C, Nishimura R, Bonow R, Carabello B, Erwin 3rd J, Gentile F . 2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2020; 77(4):450-500. DOI: 10.1016/j.jacc.2020.11.035. View

2.
Damluji A, Bandeen-Roche K, Berkower C, Boyd C, Al-Damluji M, Cohen M . Percutaneous Coronary Intervention in Older Patients With ST-Segment Elevation Myocardial Infarction and Cardiogenic Shock. J Am Coll Cardiol. 2019; 73(15):1890-1900. PMC: 7185801. DOI: 10.1016/j.jacc.2019.01.055. View

3.
Rao S, Ou F, Wang T, Roe M, Brindis R, Rumsfeld J . Trends in the prevalence and outcomes of radial and femoral approaches to percutaneous coronary intervention: a report from the National Cardiovascular Data Registry. JACC Cardiovasc Interv. 2009; 1(4):379-86. DOI: 10.1016/j.jcin.2008.05.007. View

4.
Breen K, Finnegan L, Vuckovic K, Fink A, Rosamond W, DeVon H . Multimorbidity in Patients With Acute Coronary Syndrome Is Associated With Greater Mortality, Higher Readmission Rates, and Increased Length of Stay: A Systematic Review. J Cardiovasc Nurs. 2020; 35(6):E99-E110. PMC: 7554060. DOI: 10.1097/JCN.0000000000000748. View

5.
Arnold S, Chinnakondepalli K, Spertus J, Magnuson E, Baron S, Kar S . Health Status After Transcatheter Mitral-Valve Repair in Heart Failure and Secondary Mitral Regurgitation: COAPT Trial. J Am Coll Cardiol. 2019; 73(17):2123-2132. PMC: 6499691. DOI: 10.1016/j.jacc.2019.02.010. View