Iron Status and Hemoglobin Adjustment by Altitude to Define Anemia in Children Aged 6 to 8 Months Living in Lima, Arequipa, Cusco and Puno

Overview

Journal Rev Peru Med Exp Salud Publica

Specialties General Medicine
Public Health

Date 2024 Apr 10

PMID 38597467

Authors

Juan Pablo Aparco

Gabriela Santos-Antonio

William Bautista-Olortegui

Katherine Alvis-Chirinos

Patricia Velarde-Delgado

Paul Hinojosa-Mamani

Gilmer Solis-Sanchez

Flor Eliana Santa Cruz

Nelly Zavaleta

Affiliations

Soon will be listed here.

Abstract

Objective.: To describe the iron status profile and to propose hemoglobin adjustment factors for altitude for children aged 6 to 8 months in Lima, Arequipa, Cusco and Puno.

Materials And Methods.: Cross-sectional study in children aged 6 to 8 months from four cities. We measured hemoglobin and other iron biomarkers, C-reactive protein (CRP), among others. To estimate the adjustment equation, we applied an exponential regression. We excluded children with iron deficiency (ID) and/or inflammation.

Results.: The proportions of ID were higher in Puno and Arequipa, while inflammation did not exceed 19% in any of the cities. Hemoglobin showed an exponential increase at higher altitude. The adjustment equation was: 10.34249 x (1.00007 ^ Alt).

Conclusions.: Children residing in Arequipa and Puno showed higher rates of ID and lower iron reserves; furthermore, the increase in hemoglobin by altitude was exponential, showing the need to adjust hemoglobin at altitude.

Citing Articles

Hemoglobin levels for determining anemia: new World Health Organization guidelines and adaptation of the national standard.

Gonzales G, Suarez Moreno V Rev Peru Med Exp Salud Publica. 2024; 41(2):102-104.

PMID: 39166631 PMC: 11300700. DOI: 10.17843/rpmesp.2024.412.13894.

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