» Articles » PMID: 38596986

Progress and Perspectives on Cell-free Regenerative Endodontic Therapy

Overview
Specialty Dentistry
Date 2024 Apr 10
PMID 38596986
Authors
Affiliations
Soon will be listed here.
Abstract

Although teeth with pulpitis/apical periodontitis are saved after successful endodontic therapy, they are devitalized and susceptible to reinfections and fractures. The development of biology-based approaches for dental pulp regeneration or repair is possible today because of recent advances in tissue engineering and biomaterials. Cell-free regenerative endodontic therapy offers a promising strategy for the treatment of necrotic immature permanent teeth in children and adolescents. However, studies are underway to determine whether this procedure can be applied to mature teeth.

Citing Articles

Research progress of dental pulp regeneration treatment.

Luo Z, Yu M, Shen T Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2024; 49(6):989-997.

PMID: 39311795 PMC: 11420962. DOI: 10.11817/j.issn.1672-7347.2024.240011.


The Effect of Differentiation of Human Dental Pulp Stem Cells to Glial Cells on the Sensory Nerves of the Dental Pulp.

Liu Y, Zou Y, Liu X, Wang Y, Sun J, Yuan C Int J Dent. 2024; 2024:3746794.

PMID: 38715867 PMC: 11074855. DOI: 10.1155/2024/3746794.

References
1.
Song M, Cao Y, Shin S, Shon W, Chugal N, Kim R . Revascularization-associated Intracanal Calcification: Assessment of Prevalence and Contributing Factors. J Endod. 2017; 43(12):2025-2033. DOI: 10.1016/j.joen.2017.06.018. View

2.
Paryani K, Kim S . Regenerative endodontic treatment of permanent teeth after completion of root development: a report of 2 cases. J Endod. 2013; 39(7):929-34. DOI: 10.1016/j.joen.2013.04.029. View

3.
Nagy M, Tawfik H, Hashem A, Abu-Seida A . Regenerative potential of immature permanent teeth with necrotic pulps after different regenerative protocols. J Endod. 2014; 40(2):192-8. DOI: 10.1016/j.joen.2013.10.027. View

4.
Sui B, Chen C, Kou X, Li B, Xuan K, Shi S . Pulp Stem Cell-Mediated Functional Pulp Regeneration. J Dent Res. 2018; 98(1):27-35. DOI: 10.1177/0022034518808754. View

5.
Shimizu E, Ricucci D, Albert J, Alobaid A, Gibbs J, Huang G . Clinical, radiographic, and histological observation of a human immature permanent tooth with chronic apical abscess after revitalization treatment. J Endod. 2013; 39(8):1078-83. DOI: 10.1016/j.joen.2013.04.032. View