Association of Socioeconomic Status and Overactive Bladder in US Adults: a Cross-sectional Analysis of Nationally Representative Data

Overview

Journal Front Public Health

Specialty Public Health

Date 2024 Apr 10

PMID 38596511

Authors

Weilong Lin

Taibiao Li

Zhengyuan Xu

Peixin Chen

Qianqi Zheng

Ying-Kai Hong

Wei-Juan Liu

Affiliations

Soon will be listed here.

Abstract

Background: Socioeconomic status inequality is an important variable in the emergence of urological diseases in humans. This study set out to investigate the association between the prevalence of overactive bladder (OAB) and the poverty income ratio (PIR) that served as a more influential indicator of socioeconomic status compared to education and occupation.

Method: Data from the National Health and Nutrition Examination Survey (NHANES) conducted from 2007 to 2020 were used in this cross-sectional study. The association between the PIR and OAB was examined using weighted multivariate logistic regression and weighted restricted cubic splines (RCS). Additionally, interaction analysis was used for investigation to the connections between PIR and OAB in various covariate groups in order to confirm the stability of the results.

Results: We observed a noteworthy inverse association between PIR and OAB after adjusting for potential confounding variables (OR = 0.87, 95% CI, 0.84-0.90, < 0.0001). PIR was transformed into categorical variables, and the association held steady after that (1.0 < PIR <4.0 vs. PIR ≤ 1.0, OR = 0.70, 95% CI =0.63-0.77, < 0.0001; PIR ≥ 4.0 vs. PIR ≤ 1.0, OR = 0.56, 95% CI =0.48-0.65, < 0.0001). Additionally, RCS analysis showed that PIR and OAB had a negative nonlinear response relationship. Subgroup analyses showed that the inverse association between PIR and prevalence of OAB was stronger in obese than in nonobese individuals (P for interaction < 0.05).

Conclusion: In our study, we observed a significant negative association between the PIR and the prevalence of OAB. In the future, PIR could be used as a reference standard to develop strategies to prevent and treat OAB.

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References

Zhu S, Wang Z, Tao Z, Wang S, Wang Z . Relationship Between Marijuana Use and Overactive Bladder (OAB): A Cross-Sectional Research of NHANES 2005 to 2018. Am J Med. 2022; 136(1):72-78. DOI: 10.1016/j.amjmed.2022.08.031. View

Minhas A, Jain V, Li M, Ariss R, Fudim M, Michos E . Family income and cardiovascular disease risk in American adults. Sci Rep. 2023; 13(1):279. PMC: 9822929. DOI: 10.1038/s41598-023-27474-x. View

Liberman J, Hunt T, Stewart W, Wein A, Zhou Z, Herzog A . Health-related quality of life among adults with symptoms of overactive bladder: results from a U.S. community-based survey. Urology. 2001; 57(6):1044-50. DOI: 10.1016/s0090-4295(01)00986-4. View

Ali M, Bullard K, Beckles G, Stevens M, Barker L, Narayan K . Household income and cardiovascular disease risks in U.S. children and young adults: analyses from NHANES 1999-2008. Diabetes Care. 2011; 34(9):1998-2004. PMC: 3161277. DOI: 10.2337/dc11-0792. View

Wang M, Liu Y, Ma Y, Li Y, Sun C, Cheng Y . Association Between Cancer Prevalence and Different Socioeconomic Strata in the US: The National Health and Nutrition Examination Survey, 1999-2018. Front Public Health. 2022; 10:873805. PMC: 9355719. DOI: 10.3389/fpubh.2022.873805. View

Xing D, Wang Y, Wen Y, Li Q, Feng J, Wu J . Prevalence and risk factors of overactive bladder in Chinese children: A population-based study. Neurourol Urodyn. 2019; 39(2):688-694. DOI: 10.1002/nau.24251. View

Zhu Y, Zhu Z, Chen J . Risk factors associated with the progression of overactive bladder among patients with type 2 diabetes. Int J Clin Pract. 2019; 73(11):e13395. PMC: 6851595. DOI: 10.1111/ijcp.13395. View

Dai S, Chen H, Luo T . Prevalence and factors of urinary incontinence among postpartum: systematic review and meta-analysis. BMC Pregnancy Childbirth. 2023; 23(1):761. PMC: 10612348. DOI: 10.1186/s12884-023-06059-6. View

Syan R, Zhang C, Enemchukwu E . Racial and Socioeconomic Factors Influence Utilization of Advanced Therapies in Commercially Insured OAB Patients: An Analysis of Over 800,000 OAB Patients. Urology. 2020; 142:81-86. DOI: 10.1016/j.urology.2020.04.109. View

10.

Coyne K, Zhou Z, Bhattacharyya S, Thompson C, Dhawan R, Versi E . The prevalence of nocturia and its effect on health-related quality of life and sleep in a community sample in the USA. BJU Int. 2003; 92(9):948-54. DOI: 10.1111/j.1464-410x.2003.04527.x. View

11.

Blaivas J, Panagopoulos G, Weiss J, Somaroo C . Validation of the overactive bladder symptom score. J Urol. 2007; 178(2):543-7. DOI: 10.1016/j.juro.2007.03.133. View

12.

Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U . The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society. Neurourol Urodyn. 2002; 21(2):167-78. DOI: 10.1002/nau.10052. View

13.

Kivimaki M, Batty G, Pentti J, Shipley M, Sipila P, Nyberg S . Association between socioeconomic status and the development of mental and physical health conditions in adulthood: a multi-cohort study. Lancet Public Health. 2020; 5(3):e140-e149. DOI: 10.1016/S2468-2667(19)30248-8. View

14.

Kim S, Bang W, Choi H . Analysis of the prevalence and associated factors of overactive bladder in adult Korean men. PLoS One. 2017; 12(4):e0175641. PMC: 5391112. DOI: 10.1371/journal.pone.0175641. View

15.

Peyronnet B, Mironska E, Chapple C, Cardozo L, Oelke M, Dmochowski R . A Comprehensive Review of Overactive Bladder Pathophysiology: On the Way to Tailored Treatment. Eur Urol. 2019; 75(6):988-1000. DOI: 10.1016/j.eururo.2019.02.038. View

16.

Teleman P, Lidfeldt J, Nerbrand C, Samsioe G, Mattiasson A . Overactive bladder: prevalence, risk factors and relation to stress incontinence in middle-aged women. BJOG. 2004; 111(6):600-4. DOI: 10.1111/j.1471-0528.2004.00137.x. View

17.

Hunt E, Brazendale K, Dunn C, Boutte A, Liu J, Hardin J . Income, Race and its Association with Obesogenic Behaviors of U.S. Children and Adolescents, NHANES 2003-2006. J Community Health. 2019; 44(3):507-518. PMC: 11462129. DOI: 10.1007/s10900-018-00613-6. View

18.

Albano J, Ward E, Jemal A, Anderson R, Cokkinides V, Murray T . Cancer mortality in the United States by education level and race. J Natl Cancer Inst. 2007; 99(18):1384-94. DOI: 10.1093/jnci/djm127. View

19.

Mckellar K, Bellin E, Schoenbaum E, Abraham N . Prevalence, Risk Factors, and Treatment for Overactive Bladder in a Racially Diverse Population. Urology. 2019; 126:70-75. DOI: 10.1016/j.urology.2018.12.021. View

20.

Braveman P, Cubbin C, Egerter S, Chideya S, Marchi K, Metzler M . Socioeconomic status in health research: one size does not fit all. JAMA. 2005; 294(22):2879-88. DOI: 10.1001/jama.294.22.2879. View