Renal Vein Thrombosis in a Patient Secondary to High-grade Rhabdoid Renal Cell Carcinoma: a Case Report and Review of Literature

Overview

Journal Ann Med Surg (Lond)

Publisher Wolters Kluwer

Specialty Medical Education

Date 2024 Apr 5

PMID 38576908

Authors

Manish Kc

Himal Bikram Bhattarai

Pratik Subedi

Ashutosh Kashyap

Manish Wadhwa

Dania Kaur

Sabina Koirala

Swotantra Gautam

Affiliations

Soon will be listed here.

Abstract

Introduction: Renal cell carcinoma, a common kidney tumour which is often incidentally discovered on imaging, can manifest with atypical symptoms. Renal cell carcinoma with rhabdoid features is a rare occurrence and even rarer in case of adults. Renal cell carcinoma has the tendency to form thrombus that can migrate to renal vein, inferior vena cava and even right atrium.

Case Presentation: The authors report a case of an 81-year-old male with rhabdoid renal cell carcinoma presenting with persistent cough for 6-7 months. with tumour thrombus extending into the renal vein and hepatic inferior vena cava. The patient was found feeble for the surgery and hence was treated on anticancer drugs pembrolizumab and axitinib.

Conclusion: Renal cell carcinoma has the tendency to form tumour thrombus in renal vein and inferior vena cava. Prognosis without surgical intervention in these conditions is very poor.

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