Disrupting the TGF-β-Wnt Balance to Control the Polarity of the Cystic Fibrosis Airway Epithelium
Overview
Overview
Journal
Am J Respir Cell Mol Biol
Specialties
Cell Biology
Molecular Biology
Molecular Biology
Date
2024 Apr 4
PMID
38574230
Authors
Authors
Affiliations
Affiliations
Soon will be listed here.
References
1.
Cohen J, Larson J, Killeen E, Love D, Takemaru K
. CFTR and Wnt/beta-catenin signaling in lung development. BMC Dev Biol. 2008; 8:70.
PMC: 2464600.
DOI: 10.1186/1471-213X-8-70.
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2.
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. Targeting HuR-Vav3 mRNA interaction prevents Pseudomonas aeruginosa adhesion to the cystic fibrosis airway epithelium. JCI Insight. 2023; 8(3).
PMC: 9977432.
DOI: 10.1172/jci.insight.161961.
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3.
Kramer E, Hardie W, Madala S, Davidson C, Clancy J
. Subacute TGFβ expression drives inflammation, goblet cell hyperplasia, and pulmonary function abnormalities in mice with effects dependent on CFTR function. Am J Physiol Lung Cell Mol Physiol. 2018; 315(3):L456-L465.
PMC: 6172618.
DOI: 10.1152/ajplung.00530.2017.
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4.
Bengtson C, Silswal N, Baumlin N, Yoshida M, Dennis J, Yerrathota S
. The CFTR Amplifier Nesolicaftor Rescues TGF-β1 Inhibition of Modulator-Corrected F508del CFTR Function. Int J Mol Sci. 2022; 23(18).
PMC: 9504033.
DOI: 10.3390/ijms231810956.
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5.
Shteinberg M, Haq I, Polineni D, Davies J
. Cystic fibrosis. Lancet. 2021; 397(10290):2195-2211.
DOI: 10.1016/S0140-6736(20)32542-3.
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