Multivitamin Use Among Hispanic Women of Reproductive Age in the United States, 2013-2022

Overview

Journal J Womens Health (Larchmt)

Specialty Gynecology & Obstetrics

Date 2024 Apr 2

PMID 38563830

Authors

Kaitlyn Long

Cara T Mai

Xin Yue

Lorraine F Yeung

Affiliations

Soon will be listed here.

Abstract

The U.S. Public Health Service and the Institute of Medicine recommend that all women capable of becoming pregnant consume 400 μg of folic acid daily to help prevent neural tube defects (NTDs). Hispanic women are at higher risk of having babies with NTDs than non-Hispanic White women. This study assessed multivitamin (MV) use, a main source of folic acid, among Hispanic women of reproductive age using a survey of solely U.S. Hispanic adults. MV use was assessed as part of Porter Novelli's survey, fielded annually through the largest online U.S. Hispanic panel, Offerwise's QueOpinas. During the study period of 2013-2022, 9,999 surveys were completed; selection was weighted to match the U.S. Census American Community Survey proportions. Log-binomial regression models were applied to estimate MV use trends by age groups, acculturation levels, and pregnancy intention. Among 3,700 Hispanic women of reproductive age, overall no MV use increased from 39.3% in 2013 to 54.7% in 2022 ( for trend <0.0001), especially among Hispanic women aged 18-34 years and those classified as acculturated. Among women planning to get pregnant, daily MV use was 31.1% in 2013 compared with 18.7% in 2020-2022 ( = 0.04). Given the increase in no MV use among Hispanic women of reproductive age, targeted interventions may help reach at-risk groups for NTDs prevention.

References

Yang Q, Carter H, Mulinare J, Berry R, Friedman J, Erickson J . Race-ethnicity differences in folic acid intake in women of childbearing age in the United States after folic acid fortification: findings from the National Health and Nutrition Examination Survey, 2001-2002. Am J Clin Nutr. 2007; 85(5):1409-16. DOI: 10.1093/ajcn/85.5.1409. View

deRosset L, Mullenix A, Flores A, Mattia-Dewey D, Mai C . Promotora de salud: promoting folic acid use among Hispanic women. J Womens Health (Larchmt). 2014; 23(6):525-31. PMC: 4464669. DOI: 10.1089/jwh.2013.4695. View

DAngelo D, Williams L, Morrow B, Cox S, Harris N, Harrison L . Preconception and interconception health status of women who recently gave birth to a live-born infant--Pregnancy Risk Assessment Monitoring System (PRAMS), United States, 26 reporting areas, 2004. MMWR Surveill Summ. 2007; 56(10):1-35. View

Crider K, Qi Y, Devine O, Tinker S, Berry R . Modeling the impact of folic acid fortification and supplementation on red blood cell folate concentrations and predicted neural tube defect risk in the United States: have we reached optimal prevention?. Am J Clin Nutr. 2018; 107(6):1027-1034. PMC: 6980262. DOI: 10.1093/ajcn/nqy065. View

Green-Raleigh K, Carter H, Mulinare J, Prue C, Petrini J . Trends in folic Acid awareness and behavior in the United States: the Gallup Organization for the March of Dimes Foundation surveys, 1995-2005. Matern Child Health J. 2006; 10(5 Suppl):S177-82. PMC: 1592142. DOI: 10.1007/s10995-006-0104-0. View

DeMarco M, Shafqat M, Horst M, Srinivasan S, Frayne D, Schlar L . Interventions to Increase Multivitamin Use Among Women in the Interconception Period: An IMPLICIT Network Study. Matern Child Health J. 2020; 25(2):207-213. DOI: 10.1007/s10995-020-03055-6. View

Chuang C, Hillemeier M, Dyer A, Weisman C . The relationship between pregnancy intention and preconception health behaviors. Prev Med. 2011; 53(1-2):85-8. PMC: 3143280. DOI: 10.1016/j.ypmed.2011.04.009. View

Canfield M, Ramadhani T, Shaw G, Carmichael S, Waller D, Mosley B . Anencephaly and spina bifida among Hispanics: maternal, sociodemographic, and acculturation factors in the National Birth Defects Prevention Study. Birth Defects Res A Clin Mol Teratol. 2009; 85(7):637-46. DOI: 10.1002/bdra.20582. View

Williams J, Mai C, Mulinare J, Isenburg J, Flood T, Ethen M . Updated estimates of neural tube defects prevented by mandatory folic Acid fortification - United States, 1995-2011. MMWR Morb Mortal Wkly Rep. 2015; 64(1):1-5. PMC: 4584791. View

10.

Pazol K, Robbins C, Black L, Ahrens K, Daniels K, Chandra A . Receipt of Selected Preventive Health Services for Women and Men of Reproductive Age - United States, 2011-2013. MMWR Surveill Summ. 2017; 66(20):1-31. PMC: 5879726. DOI: 10.15585/mmwr.ss6620a1. View

11.

Tinker S, Cogswell M, Devine O, Berry R . Folic acid intake among U.S. women aged 15-44 years, National Health and Nutrition Examination Survey, 2003-2006. Am J Prev Med. 2010; 38(5):534-42. DOI: 10.1016/j.amepre.2010.01.025. View

12.

Kantor E, Rehm C, Du M, White E, Giovannucci E . Trends in Dietary Supplement Use Among US Adults From 1999-2012. JAMA. 2016; 316(14):1464-1474. PMC: 5540241. DOI: 10.1001/jama.2016.14403. View

13.

Flores A, Cordero A, Dunn M, Sniezek J, Arce M, Crider K . Adding folic acid to corn Masa flour: Partnering to improve pregnancy outcomes and reduce health disparities. Prev Med. 2017; 106:26-30. PMC: 5912337. DOI: 10.1016/j.ypmed.2017.11.003. View

14.

. Recommendations for the use of folic acid to reduce the number of cases of spina bifida and other neural tube defects. MMWR Recomm Rep. 1992; 41(RR-14):1-7. View

15.

Osterman M, Hamilton B, Martin J, Driscoll A, Valenzuela C . Births: Final Data for 2020. Natl Vital Stat Rep. 2022; 70(17):1-50. View

16.

. CDC Grand Rounds: additional opportunities to prevent neural tube defects with folic acid fortification. MMWR Morb Mortal Wkly Rep. 2010; 59(31):980-4. View

17.

Tinker S, Hamner H, Qi Y, Crider K . U.S. women of childbearing age who are at possible increased risk of a neural tube defect-affected pregnancy due to suboptimal red blood cell folate concentrations, National Health and Nutrition Examination Survey 2007 to 2012. Birth Defects Res A Clin Mol Teratol. 2015; 103(6):517-26. PMC: 4515959. DOI: 10.1002/bdra.23378. View

18.

Hamner H, Cogswell M, Johnson M . Acculturation factors are associated with folate intakes among Mexican American women. J Nutr. 2011; 141(10):1889-97. DOI: 10.3945/jn.111.143412. View

19.

Velie E, Shaw G, Malcoe L, Schaffer D, Samuels S, Todoroff K . Understanding the increased risk of neural tube defect-affected pregnancies among Mexico-born women in California: immigration and anthropometric factors. Paediatr Perinat Epidemiol. 2006; 20(3):219-30. DOI: 10.1111/j.1365-3016.2006.00722.x. View

20.

Marchetta C, Hamner H . Blood folate concentrations among women of childbearing age by race/ethnicity and acculturation, NHANES 2001-2010. Matern Child Nutr. 2014; 12(1):39-50. PMC: 4514562. DOI: 10.1111/mcn.12134. View