The Association of Iron Intake and Hypertension, Does Iron Intake Decrease Blood Pressure?

Overview

Journal Cardiovasc Toxicol

Specialties Cardiology & Vascular Diseases
Toxicology

Date 2024 Apr 1

PMID 38561455

Authors

Mahdi Mousavi Mele

Atefeh Tahavorgar

Zahra Salimi

Ali Shaker

Seyed Ali Askarpour

Mohammad Keshavarz Mohammadian

Seyed Reza Mirshafaei

Zahra Saeedirad

Mahdie Torkaman

Zahra Mahmoudi

Shirin Tajadod

Sara Khoshdooz

Saeid Doaei

Akram Kooshki

Maryam Gholamalizadeh

Affiliations

Soon will be listed here.

Abstract

Previous studies reported that iron may have an indispensable role in the risk of hypertension (HTN). However, the result of the studies on the relationship between iron and risk of HTN is inconsistent. This study aimed to assess the association between the association of dietary iron intake and HTN in the Iranian population. This case-control study was conducted on 4184 people aged 35 to 70, including 1239 people with HTN and 2945 people with normal blood pressure (BP) in Sabzevar, Iran. Dietary intake was assessed using a food frequency questionnaire (FFQ). The Nutritionist IV software was used in terms of the assessment of dietary intake of iron. An inverse association was found between iron intake and HTN (OR = 0.97, CI 95%: 0.94-0.99, P = 0.04). The association remained significant after adjustment for age, gender, smoking, drinking alcohol, calorie intake, and BMI (OR = 0.94, CI 95%: 0.89-0.98, P = 0.01). As a conclusion, iron intake was inversely associated with HTN. Further longitudinal studies on the effect of iron intake on BP are required to confirm this finding.

Citing Articles

Appraising the Role of Circulating Concentrations of Micronutrients in Hypertension: A Two-sample, Multivariable Mendelian Randomization Study.

Liu Y, Bao C, Wang H, Wei D, Zhang Z Glob Heart. 2024; 19(1):81.

PMID: 39479260 PMC: 11523844. DOI: 10.5334/gh.1367.

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