Fatal Itching and Failing Liver: A Case Report and Literature Review of Rare, Atypical DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) Syndrome

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2024 Apr 1

PMID 38559511

Authors

Mohammed Abusuliman

Mahmoud Amreia

Sheema Rehman

Ammad J Chaudhary

Hazem Abosheaishaa

Taher Jamali

Amir Hanafi

Affiliations

Soon will be listed here.

Abstract

DRESS (Drug Rash with Eosinophilia and Systemic Symptoms) syndrome is a rare, life-threatening, hypersensitivity reaction. The prolonged course and non-specific symptoms of the condition make diagnosis challenging. We present a case of DRESS syndrome that was misdiagnosed as urticaria. Investigations revealed deranged liver and kidney functions and abnormal blood count. The presented case emphasizes the need to have a high suspicion for DRESS syndrome in patients who present with jaundice, generalized rash, acute renal failure, and acute liver failure.

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