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Microbial Symphony: Navigating the Intricacies of the Human Oral Microbiome and Its Impact on Health

Overview
Journal Microorganisms
Specialty Microbiology
Date 2024 Mar 28
PMID 38543622
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Abstract

This comprehensive review delves into the forefront of research on the human oral microbiome, exploring recent advancements that span microbial colonization, state-of-the-art detection methodologies, and the complex interplay involved in disease progression. Through an exhaustive analysis of the contemporary literature, we illuminate the dynamic orchestration of microbial communities within the oral cavity, underscoring their pivotal role in health and disease. Cutting-edge detection techniques, including metagenomics and high-throughput sequencing, are discussed regarding their transformative impact on understanding the intricacies of oral microbial ecosystems. As we stand on the cusp of a new decade, this review anticipates a paradigm shift in the field, emphasizing the potential for rapid identification and targeted management of detrimental oral microorganisms. Insights gained from this exploration not only contribute to our fundamental understanding of the oral microbiome but also hold promise for the development of innovative therapeutic strategies to maintain oral health. This article aims to serve as a valuable resource for researchers, clinicians, and public health professionals engaged in unraveling the mysteries of the microbial symphony within the human oral cavity.

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References
1.
Aas J, Paster B, Stokes L, Olsen I, Dewhirst F . Defining the normal bacterial flora of the oral cavity. J Clin Microbiol. 2005; 43(11):5721-32. PMC: 1287824. DOI: 10.1128/JCM.43.11.5721-5732.2005. View

2.
Walujkar S, Dhotre D, Marathe N, Lawate P, Bharadwaj R, Shouche Y . Characterization of bacterial community shift in human Ulcerative Colitis patients revealed by Illumina based 16S rRNA gene amplicon sequencing. Gut Pathog. 2014; 6:22. PMC: 4094692. DOI: 10.1186/1757-4749-6-22. View

3.
Marsh P, Head D, Devine D . Ecological approaches to oral biofilms: control without killing. Caries Res. 2015; 49 Suppl 1:46-54. DOI: 10.1159/000377732. View

4.
Docktor M, Paster B, Abramowicz S, Ingram J, Wang Y, Correll M . Alterations in diversity of the oral microbiome in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2011; 18(5):935-42. PMC: 4208308. DOI: 10.1002/ibd.21874. View

5.
Gohl D, Vangay P, Garbe J, MacLean A, Hauge A, Becker A . Systematic improvement of amplicon marker gene methods for increased accuracy in microbiome studies. Nat Biotechnol. 2016; 34(9):942-9. DOI: 10.1038/nbt.3601. View