Survey in Captive Non-Human Primates, Italy

Overview

Journal Animals (Basel)

Date 2024 Mar 28

PMID 38539979

Authors

Vittorio Sarchese

Federica Di Profio

Andrea Palombieri

Klaus Gunther Friedrich

Serena Robetto

Krisztian Banyai

Fulvio Marsilio

Vito Martella

Barbara Di Martino

Affiliations

Soon will be listed here.

Abstract

Circoviruses (CVs) and cycloviruses (CyVs), members of the family , have been identified only occasionally in non-human primates (NHPs). In this study, we investigated the presence and genetic features of these viruses in 48 NHPs housed in the Bioparco-Rome Zoological Garden (Italy) and in the Anima Natura Wild Sanctuary Semproniano (Grosseto, Italy), testing fecal, saliva, and serum samples with a broadly reactive consensus nested PCR able of amplifying a partial region of the replicase (Rep) gene of members of the family . Viral DNA was detected in a total of 10 samples, including a saliva swab and 9 fecal samples collected, respectively from five Japanese macaques () and four mandrills (), with an overall prevalence of 18.7% (9/48). On genome sequencing, five strains revealed the highest nucleotide identity (98.3-98.6%) to a CyV strain (RI196/ITA) detected in the intestinal content of a Maltese wall lizard () in Italy. Although the origin of the Italian NHP strains, genetically distant from previously detected NHP CyVs, is uncertain, our results also highlight that the virome of captive animals is modulated by the different dietary and environmental sources of exposure.

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