» Articles » PMID: 38534601

Gellan Gum As a Unique Microbial Polysaccharide: Its Characteristics, Synthesis, and Current Application Trends

Overview
Journal Gels
Date 2024 Mar 27
PMID 38534601
Authors
Affiliations
Soon will be listed here.
Abstract

Gellan gum (GG) is a linear, negatively charged exopolysaccharide that is biodegradable and non-toxic. When metallic ions are present, a hard and transparent gel is produced, which remains stable at a low pH. It exhibits high water solubility, can be easily bio-fabricated, demonstrates excellent film/hydrogel formation, is biodegradable, and shows biocompatibility. These characteristics render GG a suitable option for use in food, biomedical, and cosmetic fields. Thus, this review paper offers a concise summary of microbial polysaccharides. Moreover, an in-depth investigation of trends in different facets of GG, such as biosynthesis, chemical composition, and physical and chemical properties, is emphasized. In addition, this paper highlights the process of extracting and purifying GG. Furthermore, an in-depth discussion of the advantages and disadvantages of GG concerning other polysaccharides is presented. Moreover, the utilization of GG across different industries, such as food, medicine, pharmaceuticals, cosmetics, etc., is thoroughly examined and will greatly benefit individuals involved in this field who are seeking fresh opportunities for innovative projects in the future.

Citing Articles

Microbial-Derived Biopolymers: A Pathway to Sustainable Civil Engineering.

Kannan G, Sujatha E, Almajed A, Moghal A Polymers (Basel). 2025; 17(2.

PMID: 39861245 PMC: 11768209. DOI: 10.3390/polym17020172.


A Natural Carbon Encapsulated in Gellan-Based Hydrogel Particles Designed for Environmental Challenges.

Tincu Iurciuc C, Hamcerencu M, Secula M, Stan C, Albu C, Popa M Gels. 2024; 10(11).

PMID: 39590069 PMC: 11593462. DOI: 10.3390/gels10110713.


Advances in Microbial Exopolysaccharides: Present and Future Applications.

Nguyen H, Pham T, Nguyen P, Le-Buanec H, Rabetafika H, Razafindralambo H Biomolecules. 2024; 14(9).

PMID: 39334928 PMC: 11430787. DOI: 10.3390/biom14091162.

References
1.
Huang J, Zhu S, Li C, Zhang C, Ji Y . Cost-effective optimization of gellan gum production by using corn steep liquor. Prep Biochem Biotechnol. 2019; 50(2):191-197. DOI: 10.1080/10826068.2019.1692215. View

2.
Muthukumar T, Song J, Khang G . Biological Role of Gellan Gum in Improving Scaffold Drug Delivery, Cell Adhesion Properties for Tissue Engineering Applications. Molecules. 2019; 24(24). PMC: 6943741. DOI: 10.3390/molecules24244514. View

3.
Shahbazizadeh S, Naji-Tabasi S, Shahidi-Noghabi M, Pourfarzad A . Development of cress seed gum hydrogel and investigation of its potential application in the delivery of curcumin. J Sci Food Agric. 2021; 101(15):6505-6513. DOI: 10.1002/jsfa.11322. View

4.
Martins L, Sa-Correia I . Gellan gum biosynthetic enzymes in producing and nonproducing variants of Pseudomonas elodea. Biotechnol Appl Biochem. 1991; 14(3):357-64. View

5.
Mohammed A, Naveed M, Jost N . Polysaccharides; Classification, Chemical Properties, and Future Perspective Applications in Fields of Pharmacology and Biological Medicine (A Review of Current Applications and Upcoming Potentialities). J Polym Environ. 2021; 29(8):2359-2371. PMC: 7838237. DOI: 10.1007/s10924-021-02052-2. View