The Enterics for Global Health (EFGH) Surveillance Study in Pakistan

Overview

Journal Open Forum Infect Dis

Specialty Infectious Diseases

Date 2024 Mar 27

PMID 38532950

Authors

Naveed Ahmed

Mohammad Tahir Yousafzai

Farah Naz Qamar

Affiliations

Soon will be listed here.

Abstract

Background: The Enterics for Global Health (EFGH) surveillance study is a longitudinal multicountry study that aims to estimate incidence rates and document consequences of diarrhea within 7 countries in Africa, Asia, and Latin America. In addition to a high incidence of childhood diarrhea, Pakistan is facing a problem of antimicrobial resistance in urban and peri-urban areas of Karachi.

Methods: In Pakistan, EFGH will be conducted in Karachi, which is one of the metropolitan cities bordering the Arabian Sea and has a diverse population of 1.6 million according to the 2017 population census. The study aims to enroll 1400 children aged 6-35 months over 2 years (2022-2024) from 6 health care facilities (Abbasi Shaheed Hospital, Khidmat-e-Alam Medical Centre, Sindh Government Hospital Korangi 5, Sindh Government Hospital Ibrahim Hyderi, Ali Akbar Shah VPT Center, and Bhains Colony VPT Center) situated in Nazimabad and Bin-Qasim town. Moreover, population enumeration and health care utilization surveys from a defined catchment area of health facilities will be conducted to estimate the diarrhea incidence rates.

Conclusions: The study will provide critical data to policy-makers about the burden of and antimicrobial resistance, which is essential for planning vaccine trials.

Citing Articles

Optimizing Vaccine Trials for Enteric Diseases: The Enterics for Global Health (EFGH) Surveillance Study.

Vannice K, MacLennan C, Long J, Steele A Open Forum Infect Dis. 2024; 11(Suppl 1):S1-S5.

PMID: 38532964 PMC: 10962720. DOI: 10.1093/ofid/ofad586.

Quantifying the Cost of Diarrhea in the Enterics for Global Health (EFGH) Surveillance Study.

Morozoff C, Ahmed N, Chinkhumba J, Islam M, Jallow A, Ogwel B Open Forum Infect Dis. 2024; 11(Suppl 1):S41-S47.

PMID: 38532961 PMC: 10962725. DOI: 10.1093/ofid/ofad575.

Data Management in Multicountry Consortium Studies: The Enterics For Global Health (EFGH) Surveillance Study Example.

Feutz E, Biswas P, Ndeketa L, Ogwel B, Onwuchekwa U, Sarwar G Open Forum Infect Dis. 2024; 11(Suppl 1):S48-S57.

PMID: 38532952 PMC: 10962719. DOI: 10.1093/ofid/ofad573.

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