Proceedings of the 2024 North American Society of Head and Neck Pathology Companion Meeting, Baltimore, MD, March 24, 2024: Navigating Ancillary Studies in Basaloid/Blue Salivary Tumors

Overview

Journal Head Neck Pathol

Specialties Oncology
Pathology

Date 2024 Mar 25

PMID 38526755

Authors

Kristine S Wong

Affiliations

Soon will be listed here.

Abstract

Background: Basaloid salivary tumors can demonstrate significant morphologic overlap and be challenging to diagnose.

Methods: A review of select ancillary studies in basaloid salivary tumors was performed.

Results: A number of immunohistochemical stains, including PLAG1, HMGA2, β-catenin, MYB, and RAS Q61R, have been more recently incorporated into the diagnostic workup of basaloid salivary tumors.

Conclusions: Although reported variability in their performance has perhaps limited their widespread adoption, these immunohistochemical studies can nevertheless be useful in supporting pathologic diagnoses, particularly when considered in more specific differentials or when used as a panel with other markers.

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