» Articles » PMID: 38515633

Plant-based Diets in Patients with Chronic Kidney Disease

Overview
Date 2024 Mar 22
PMID 38515633
Authors
Affiliations
Soon will be listed here.
Abstract

Dietary protein restriction has been considered to be a nutritional-related strategy to reduce risk for end-stage kidney disease among patients with non-dialysis-dependent chronic kidney disease (CKD). However, there is insufficient evidence to recommend a particular type of protein to slow down the CKD progression. Recently, various plant-based diets could demonstrate some additional benefits such as a blood pressure-lowering effect, a reduction of metabolic acidosis as well as hyperphosphatemia, and gut-derived uremic toxins. Furthermore, the former concerns about the risk of undernutrition and hyperkalemia observed with plant-based diets may be inconsistent in real clinical practice. In this review, we summarize the current evidence of the proposed pleiotropic effects of plant-based diets and their associations with clinical outcomes among pre-dialysis CKD patients.

Citing Articles

Effects of Dietary Fiber Supplementation on Modulating Uremic Toxins and Inflammation in Chronic Kidney Disease Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Wathanavasin W, Cheungpasitporn W, Thongprayoon C, Fulop T Toxins (Basel). 2025; 17(2).

PMID: 39998074 PMC: 11860371. DOI: 10.3390/toxins17020057.


Dietary Patterns, Kidney Function, and Sarcopenia in Chronic Kidney Disease.

Kim J, Yang S Nutrients. 2025; 17(3).

PMID: 39940262 PMC: 11821004. DOI: 10.3390/nu17030404.

References
1.
Goraya N, Simoni J, Jo C, Wesson D . Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate. Kidney Int. 2014; 86(5):1031-8. DOI: 10.1038/ki.2014.83. View

2.
Mathai J, Liu Y, Stein H . Values for digestible indispensable amino acid scores (DIAAS) for some dairy and plant proteins may better describe protein quality than values calculated using the concept for protein digestibility-corrected amino acid scores (PDCAAS). Br J Nutr. 2017; 117(4):490-499. DOI: 10.1017/S0007114517000125. View

3.
Cupisti A, Morelli E, Meola M, Barsotti M, Barsotti G . Vegetarian diet alternated with conventional low-protein diet for patients with chronic renal failure. J Ren Nutr. 2002; 12(1):32-7. DOI: 10.1053/jren.2002.29595. View

4.
Scialla J, Anderson C . Dietary acid load: a novel nutritional target in chronic kidney disease?. Adv Chronic Kidney Dis. 2013; 20(2):141-9. PMC: 3604792. DOI: 10.1053/j.ackd.2012.11.001. View

5.
Tuttle K, Milton J, Packard D, Shuler L, Short R . Dietary amino acids and blood pressure: a cohort study of patients with cardiovascular disease. Am J Kidney Dis. 2012; 59(6):803-9. DOI: 10.1053/j.ajkd.2011.12.026. View