DiGAlign: Versatile and Interactive Visualization of Sequence Alignment for Comparative Genomics

Overview

Journal Microbes Environ

Specialty Environmental Health

Date 2024 Mar 20

PMID 38508742

Authors

Yosuke Nishimura

Kohei Yamada

Yusuke Okazaki

Hiroyuki Ogata

Affiliations

Soon will be listed here.

Abstract

With the explosion of available genomic information, comparative genomics has become a central approach to understanding microbial ecology and evolution. We developed DiGAlign (https://www.genome.jp/digalign/), a web server that provides versatile functionality for comparative genomics with an intuitive interface. It allows the user to perform the highly customizable visualization of a synteny map by simply uploading nucleotide sequences of interest, ranging from a specific region to the whole genome landscape of microorganisms and viruses. DiGAlign will serve a wide range of biological researchers, particularly experimental biologists, with multifaceted features that allow the rapid characterization of genomic sequences of interest and the generation of a publication-ready figure.

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