Melanocytic Nevus of the Superior Conjunctival Fornix: A Case Report

Overview

Journal Case Rep Ophthalmol

Specialty Ophthalmology

Date 2024 Mar 19

PMID 38500543

Authors

Modupe O Adetunji

Thomas J Cummings

Miguel A Materin

Arpita S Maniar

Affiliations

Soon will be listed here.

Abstract

Introduction: Conjunctival nevi are benign tumors that are commonly located at the nasal or temporal limbus and rarely in the fornix or tarsus. We report a case of a patient presenting with a solitary compound cystic nevus of the conjunctival fornix in the background of bilateral complexion-associated melanosis.

Case Presentation: A 71-year-old African-American female was referred for evaluation of an incidentally noted melanocytic lesion of the right conjunctival fornix. The patient underwent an excisional biopsy, revealing histological features consistent with a compound cystic nevus.

Conclusion: This finding is noteworthy due to the rarity of conjunctival nevi originating in the fornix. The case underscores the importance of excisional biopsy in evaluating conjunctival forniceal melanocytic lesions to exclude malignant melanoma, a critical consideration for prognosis.

References

Shields C, Belinsky I, Romanelli-Gobbi M, Guzman J, Mazzuca Jr D, Ross Green W . Anterior segment optical coherence tomography of conjunctival nevus. Ophthalmology. 2010; 118(5):915-9. DOI: 10.1016/j.ophtha.2010.09.016. View

Sayed-Ahmed I, Murillo J, Monsalve P, Ulloa J, Fernandez M, Wong J . Blue Nevi of the Ocular Surface: Clinical Characteristics, Pathologic Features, and Clinical Course. Ophthalmology. 2018; 125(8):1189-1198. PMC: 6056321. DOI: 10.1016/j.ophtha.2018.02.006. View

Levecq L, De Potter P, Jamart J . Conjunctival nevi clinical features and therapeutic outcomes. Ophthalmology. 2009; 117(1):35-40. DOI: 10.1016/j.ophtha.2009.06.018. View

Dalla Pozza G, Ghirlando A, Busato F, Midena E . Reconstruction of conjunctiva with amniotic membrane after excision of large conjunctival melanoma: a long-term study. Eur J Ophthalmol. 2005; 15(4):446-50. DOI: 10.1177/112067210501500404. View

Shields C, Fasiuddin A, Fasiudden A, Mashayekhi A, Shields J . Conjunctival nevi: clinical features and natural course in 410 consecutive patients. Arch Ophthalmol. 2004; 122(2):167-75. DOI: 10.1001/archopht.122.2.167. View

Yazici B, Dolar Bilge A, Yagci A, Naqadan F, Altintepe F . Melanocytic Nevus of the Tarsal Conjunctiva. Balkan Med J. 2016; 33(4):477-9. PMC: 5001831. DOI: 10.5152/balkanmedj.2016.150317. View

Zembowicz A, Mandal R, Choopong P . Melanocytic lesions of the conjunctiva. Arch Pathol Lab Med. 2010; 134(12):1785-92. DOI: 10.5858/2009-0522-RAR.1. View

Furdova A, Czanner G, Koller J, Vesely P, Furda R, Pridavkova Z . Amniotic membrane application in surgical treatment of conjunctival tumors. Sci Rep. 2023; 13(1):2835. PMC: 9938263. DOI: 10.1038/s41598-023-30050-y. View

Shields C, Markowitz J, Belinsky I, Schwartzstein H, George N, Lally S . Conjunctival melanoma: outcomes based on tumor origin in 382 consecutive cases. Ophthalmology. 2010; 118(2):389-95.e1-2. DOI: 10.1016/j.ophtha.2010.06.021. View

10.

Shields C, Regillo A, Mellen P, Kaliki S, Lally S, Shields J . Giant conjunctival nevus: clinical features and natural course in 32 cases. JAMA Ophthalmol. 2013; 131(7):857-63. DOI: 10.1001/jamaophthalmol.2013.160. View

11.

Buckman G, Jakobiec F, Folberg R, McNally L . Melanocytic nevi of the palpebral conjunctiva. An extremely rare location usually signifying melanoma. Ophthalmology. 1988; 95(8):1053-7. DOI: 10.1016/s0161-6420(88)33059-9. View