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Management of Anhedonia After Epilepsy Surgery

Overview
Specialty Psychology
Date 2024 Mar 18
PMID 38495401
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Abstract

Anhedonia is clinically defined as difficulty or inability to feel pleasure or to be motivated to perform activities that were previously pleasurable. Anhedonia is a core feature of depressive disorders but can be present in other conditions such as substance use and anxiety disorders. Herein we report the case of a 34-year-old female who developed marked anhedonia after left cortico-amygdalohippocampectomy. Despite optimal seizure control, the person struggled with anhedonia and other depressive symptoms. After ruling out medico-neurologic complications, she was prescribed with a selective serotonin reuptake inhibitor and cognitive-behavioral therapy. Anhedonia can be a challenging neuropsychiatric presentation that requires ruling out the effects of antiseizure medications, neurosurgery, and other drugs before prescribing antidepressants.

References
1.
Koch-Stoecker S, Bien C, Schulz R, May T . Psychiatric lifetime diagnoses are associated with a reduced chance of seizure freedom after temporal lobe surgery. Epilepsia. 2017; 58(6):983-993. DOI: 10.1111/epi.13736. View

2.
Kanner A . Most antidepressant drugs are safe for patients with epilepsy at therapeutic doses: A review of the evidence. Epilepsy Behav. 2016; 61:282-286. DOI: 10.1016/j.yebeh.2016.03.022. View

3.
Castano-Monsalve B . [Antidepressants in epilepsy]. Rev Neurol. 2013; 57(3):117-22. View

4.
Macrodimitris S, Sherman E, Forde S, Tellez-Zenteno J, Metcalfe A, Hernandez-Ronquillo L . Psychiatric outcomes of epilepsy surgery: a systematic review. Epilepsia. 2011; 52(5):880-90. DOI: 10.1111/j.1528-1167.2011.03014.x. View

5.
Guineau M, Ikani N, Rinck M, Collard R, van Eijndhoven P, Tendolkar I . Anhedonia as a transdiagnostic symptom across psychological disorders: a network approach. Psychol Med. 2022; 53(9):3908-3919. PMC: 10317820. DOI: 10.1017/S0033291722000575. View