Evaluation of Factors Influencing Handgrip Strength Asymmetry in Older Peruvian Adults

Overview

Journal Ann Geriatr Med Res

Specialty Geriatrics

Date 2024 Mar 15

PMID 38486469

Authors

Alba Zevallos

Renzo Pajuelo-Vasquez

Kiara Camacho-Caballero

Rodrigo Corcuera-Ciudad

Paola Goicochea-Romero

Wendy Gutierrez-Baca

Diego Chambergo-Michilot

Jose F Parodi

Fernando M Runzer-Colmenares

Affiliations

Soon will be listed here.

Abstract

Background: Sarcopenia is a musculoskeletal disease involving the reduction of muscle mass, strength, and performance. Handgrip strength (HGS) measurements included in frailty assessments are great biomarkers of aging and are related to functional deficits. We assessed the association between potential influencing factors and HGS asymmetry in older Peruvian adults.

Methods: We used a database of the Peruvian Naval Medical Center "Cirujano Santiago Távara" located in Callao, Peru. All the patients included were ≥60 years old and had an HGS measurement in the dominant and non-dominant hand.

Results: From a total of 1,468 patients, 74.66% had HGS asymmetry. After adjustment, calf circumference weakness (adjusted prevalence ratio [aPR]=1.08; 95% confidence interval [CI], 1.01-1.15), falls risk (aPR = 1.08; 95% CI, 1.02-1.16), and an altered Lawton index (aPR=0.92; 95% CI, 0.84-0.99) were associated with HGS asymmetry.

Conclusion: Our findings suggest that HGS asymmetry should be measured along with other geriatric assessments used to evaluate health outcomes in the elderly to enhance health promotion and prevention aimed at preserving muscle strength to curb functional limitations in the elderly.

References

Go Y, Lee D, Lee H . Association between handgrip strength asymmetry and falls in elderly Koreans: A nationwide population-based cross-sectional study. Arch Gerontol Geriatr. 2021; 96:104470. DOI: 10.1016/j.archger.2021.104470. View

Landi F, Onder G, Russo A, Liperoti R, Tosato M, Martone A . Calf circumference, frailty and physical performance among older adults living in the community. Clin Nutr. 2013; 33(3):539-44. DOI: 10.1016/j.clnu.2013.07.013. View

Mortazavi S, Shati M, Keshtkar A, Malakouti S, Bazargan M, Assari S . Defining polypharmacy in the elderly: a systematic review protocol. BMJ Open. 2016; 6(3):e010989. PMC: 4809106. DOI: 10.1136/bmjopen-2015-010989. View

McLeod M, Breen L, Hamilton D, Philp A . Live strong and prosper: the importance of skeletal muscle strength for healthy ageing. Biogerontology. 2016; 17(3):497-510. PMC: 4889643. DOI: 10.1007/s10522-015-9631-7. View

Yang N, Hsu N, Lin C, Chen H, Tsao H, Lo S . Relationship between muscle strength and fall episodes among the elderly: the Yilan study, Taiwan. BMC Geriatr. 2018; 18(1):90. PMC: 5899404. DOI: 10.1186/s12877-018-0779-2. View

Merchant R, Chan Y, Hui R, Lim J, Kwek S, Seetharaman S . Possible Sarcopenia and Impact of Dual-Task Exercise on Gait Speed, Handgrip Strength, Falls, and Perceived Health. Front Med (Lausanne). 2021; 8:660463. PMC: 8086796. DOI: 10.3389/fmed.2021.660463. View

Xue Q . The frailty syndrome: definition and natural history. Clin Geriatr Med. 2010; 27(1):1-15. PMC: 3028599. DOI: 10.1016/j.cger.2010.08.009. View

Phu S, Kirk B, Bani Hassan E, Vogrin S, Zanker J, Bernardo S . The diagnostic value of the Short Physical Performance Battery for sarcopenia. BMC Geriatr. 2020; 20(1):242. PMC: 7359583. DOI: 10.1186/s12877-020-01642-4. View

Parker K, Rhee Y, Tomkinson G, Vincent B, OConnor M, McGrath R . Handgrip Weakness and Asymmetry Independently Predict the Development of New Activity Limitations: Results from Analyses of Longitudinal Data from the US Health and Retirement Study. J Am Med Dir Assoc. 2020; 22(4):821-826.e1. DOI: 10.1016/j.jamda.2020.11.006. View

10.

McGrath R, Blackwell T, Ensrud K, Vincent B, Cawthon P . The Associations of Handgrip Strength and Leg Extension Power Asymmetry on Incident Recurrent Falls and Fractures in Older Men. J Gerontol A Biol Sci Med Sci. 2021; 76(9):e221-e227. PMC: 8499308. DOI: 10.1093/gerona/glab133. View

11.

Pipinos I, Judge A, Selsby J, Zhu Z, Swanson S, Nella A . The myopathy of peripheral arterial occlusive disease: Part 2. Oxidative stress, neuropathy, and shift in muscle fiber type. Vasc Endovascular Surg. 2008; 42(2):101-12. DOI: 10.1177/1538574408315995. View

12.

Runzer-Colmenares F, Samper-Ternent R, Al Snih S, Ottenbacher K, Parodi J, Wong R . Prevalence and factors associated with frailty among Peruvian older adults. Arch Gerontol Geriatr. 2013; 58(1):69-73. PMC: 3808461. DOI: 10.1016/j.archger.2013.07.005. View

13.

Schlichthorst M, Sanci L, Pirkis J, Spittal M, Hocking J . Why do men go to the doctor? Socio-demographic and lifestyle factors associated with healthcare utilisation among a cohort of Australian men. BMC Public Health. 2017; 16(Suppl 3):1028. PMC: 5103250. DOI: 10.1186/s12889-016-3706-5. View

14.

Rothman M, Leo-Summers L, Gill T . Prognostic significance of potential frailty criteria. J Am Geriatr Soc. 2008; 56(12):2211-16. PMC: 2782664. DOI: 10.1111/j.1532-5415.2008.02008.x. View

15.

Johnston M, Crilly M, Black C, Prescott G, Mercer S . Defining and measuring multimorbidity: a systematic review of systematic reviews. Eur J Public Health. 2018; 29(1):182-189. DOI: 10.1093/eurpub/cky098. View

16.

Bouchard D, Heroux M, Janssen I . Association between muscle mass, leg strength, and fat mass with physical function in older adults: influence of age and sex. J Aging Health. 2010; 23(2):313-28. DOI: 10.1177/0898264310388562. View

17.

Brawley L, Rejeski W, King A . Promoting physical activity for older adults: the challenges for changing behavior. Am J Prev Med. 2003; 25(3 Suppl 2):172-83. DOI: 10.1016/s0749-3797(03)00182-x. View

18.

McGrath R, Vincent B, Jurivich D, Hackney K, Tomkinson G, Dahl L . Handgrip Strength Asymmetry and Weakness Together Are Associated With Functional Disability in Aging Americans. J Gerontol A Biol Sci Med Sci. 2020; 76(2):291-296. DOI: 10.1093/gerona/glaa100. View

19.

Rijk J, Roos P, Deckx L, van den Akker M, Buntinx F . Prognostic value of handgrip strength in people aged 60 years and older: A systematic review and meta-analysis. Geriatr Gerontol Int. 2015; 16(1):5-20. DOI: 10.1111/ggi.12508. View

20.

Urrunaga-Pastor D, Moncada-Mapelli E, Runzer-Colmenares F, Bailon-Valdez Z, Samper-Ternent R, Rodriguez-Manas L . Factors associated with poor balance ability in older adults of nine high-altitude communities. Arch Gerontol Geriatr. 2018; 77:108-114. DOI: 10.1016/j.archger.2018.04.013. View