Bacterial Capsules: Occurrence, Mechanism, and Function

Overview

Journal NPJ Biofilms Microbiomes

Date 2024 Mar 14

PMID 38480745

Authors

Shuji Gao

Wenjie Jin

Yingying Quan

Yue Li

Yamin Shen

Shuo Yuan

Li Yi

Yuxin Wang

Yang Wang

Affiliations

Soon will be listed here.

Abstract

In environments characterized by extended multi-stress conditions, pathogens develop a variety of immune escape mechanisms to enhance their ability to infect the host. The capsules, polymers that bacteria secrete near their cell wall, participates in numerous bacterial life processes and plays a crucial role in resisting host immune attacks and adapting to their niche. Here, we discuss the relationship between capsules and bacterial virulence, summarizing the molecular mechanisms of capsular regulation and pathogenesis to provide new insights into the research on the pathogenesis of pathogenic bacteria.

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