Mass Spectrometry Strategies for -Glycoproteomics

Overview

Journal Cells

Publisher MDPI

Specialties Biochemistry
Biophysics
Cell Biology
Molecular Biology

Date 2024 Mar 13

PMID 38474358

Authors

Amanda Helms

Jennifer S Brodbelt

Affiliations

Soon will be listed here.

Abstract

Glycoproteomics has accelerated in recent decades owing to numerous innovations in the analytical workflow. In particular, new mass spectrometry strategies have contributed to inroads in -glycoproteomics, a field that lags behind -glycoproteomics due to several unique challenges associated with the complexity of -glycosylation. This review will focus on progress in sample preparation, enrichment strategies, and MS/MS techniques for the identification and characterization of -glycoproteins.

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