Updates in Diagnosis and Endoscopic Management of Cholangiocarcinoma

Overview

Journal Diagnostics (Basel)

Specialty Radiology

Date 2024 Mar 13

PMID 38472961

Authors

Roxana-Luiza Caragut

Madalina Ilie

Teodor Cabel

Deniz Gunsahin

Afrodita Panaitescu

Christopher Pavel

Oana Mihaela Plotogea

Ecaterina Mihaela Rinja

Gabriel Constantinescu

Vasile Sandru

Affiliations

Soon will be listed here.

Abstract

Cholangiocarcinoma (CCA) is an adenocarcinoma originating from the epithelial cells of the bile ducts/hepatocytes or peribiliary glands. There are three types of cholangiocarcinoma: intrahepatic, perihilar and distal. CCA represents approximately 3% of the gastrointestinal malignancies. The incidence of CCA is higher in regions of the Eastern world compared to the Western countries. There are multiple risk factors associated with cholangiocarcinoma such as liver fluke, primary sclerosing cholangitis, chronic hepatitis B, liver cirrhosis and non-alcoholic fatty liver disease. Endoscopy plays an important role in the diagnosis and management of cholangiocarcinoma. The main endoscopic methods used for diagnosis, biliary drainage and delivering intrabiliary local therapies are endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. The purpose of this review is to analyze the current data found in literature about cholangiocarcinoma, with a focus on the actual diagnostic tools and endoscopic management options.

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