Whole-Genome DNA Methylation Profiling of Intrahepatic Cholangiocarcinoma Reveals Prognostic Subtypes with Distinct Biological Drivers

Overview

Journal Cancer Res

Specialty Oncology

Date 2024 Mar 12

PMID 38471085

Authors

Haotian Liao

Xing Chen

Haichuan Wang

Youpei Lin

Lu Chen

Kefei Yuan

Mingheng Liao

Hanyu Jiang

Jiajie Peng

Zhenru Wu

Jiwei Huang

Jiaxin Li

Yong Zeng

Affiliations

Soon will be listed here.

Abstract

Significance: Characterization of the DNA methylome of intrahepatic cholangiocarcinoma integrated with genomic, transcriptomic, and proteomic analyses uncovers molecular mechanisms affected by genome-wide DNA methylation alterations, providing a resource for identifying potential therapeutic targets.

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