Dural Composite Hemangioendothelioma: The First Intracranial Case

Overview

Journal Surg Neurol Int

Specialty Neurology

Date 2024 Mar 12

PMID 38468685

Authors

Alice Liu

Joshua S Bauer

Chun-Chieh Lin

Geoff Appelboom

George Zanazzi

Affiliations

Soon will be listed here.

Abstract

Background: Composite hemangioendothelioma (CHE) is a rare, locally aggressive neoplasm of intermediate malignant potential. It is composed of a mixture of vascular tumors with a predilection for the dermis and subcutis of the extremities.

Case Description: In this report, we describe a 41-year-old man who presented with a 2-month history of headache, dizziness, and intermittent seizures. Magnetic resonance imaging showed a hemorrhagic, multilobulated, and dural-based mass with extension into the calvarium. The mass measured 10.3 × 4.8 × 4 cm along the interhemispheric fissure and encased the superior sagittal sinus. Excision was performed, and histopathologic examination revealed a heterogeneous mixture of vascular components consisting of epithelioid hemangioendothelioma, retiform hemangioendothelioma, and hemangioma. This is the first report of a primary intracranial CHE.

Conclusion: The spectrum of mesenchymal neoplasms within the cranium expands to encompass CHE.

References

Utas S, Canoz O, Ferahbas A, Ozcan N . Composite cutaneous haemangioendothelioma treated with interferon. J Eur Acad Dermatol Venereol. 2008; 22(4):503-5. DOI: 10.1111/j.1468-3083.2007.02366.x. View

Langguth P, Salehi Ravesh M, Haneya A, Both M . Composite hemangioendothelioma: the first case of a right atrioventricular pericardial tumour. Eur Heart J Case Rep. 2020; 4(3):1. PMC: 7319823. DOI: 10.1093/ehjcr/ytaa110. View

Yamamoto F, Yamagiwa H, Iwamoto F, Kasugai T . [A Case of Primary Intracranial Epithelioid Hemangioendothelioma]. No Shinkei Geka. 2018; 46(1):35-40. DOI: 10.11477/mf.1436203671. View

Mohan S M, Symss N, Pande A, Chakravarthy V, Ramamurthi R . Intracranial epithelioid hemangioendothelioma. Childs Nerv Syst. 2008; 24(7):863-8. DOI: 10.1007/s00381-008-0634-4. View

Tammam A, Lewis P, Crockard H . Cerebello-pontine angle epithelioid haemangioendothelioma in a 4-year-old boy. Childs Nerv Syst. 1998; 13(11-12):648-50. DOI: 10.1007/s003810050162. View

Kim I, Cho H, Jung B, Pae S, Cho H, Seo J . Retiform hemangioendothelioma in the infratemporal fossa and buccal area: a case report and literature review. J Korean Assoc Oral Maxillofac Surg. 2016; 42(5):307-314. PMC: 5104875. DOI: 10.5125/jkaoms.2016.42.5.307. View

Liau J, Lee F, Chiu C, Chen J, Hsiao T . Composite hemangioendothelioma presenting as a scalp nodule with alopecia. J Am Acad Dermatol. 2013; 69(2):e98-9. DOI: 10.1016/j.jaad.2012.08.044. View

Antonescu C, Dickson B, Sung Y, Zhang L, Suurmeijer A, Stenzinger A . Recurrent YAP1 and MAML2 Gene Rearrangements in Retiform and Composite Hemangioendothelioma. Am J Surg Pathol. 2020; 44(12):1677-1684. PMC: 7773139. DOI: 10.1097/PAS.0000000000001575. View

Hardisson D, Prim M, de Diego J, Patron M, Escribano A, Rabanal I . Kaposiform hemangioendothelioma of the external auditory canal in an adult. Head Neck. 2002; 24(6):614-7. DOI: 10.1002/hed.10074. View

10.

Rath S, Mohanty B, Syasamal B . Cerebral haemangio-endothelioma. J Indian Med Assoc. 1970; 54(8):372-3. View

11.

Sumrall A, Fredericks R, Berthold A, Shumaker G . Lenalidomide stops progression of multifocal epithelioid hemangioendothelioma including intracranial disease. J Neurooncol. 2009; 97(2):275-7. DOI: 10.1007/s11060-009-0017-z. View

12.

Nora F, Scheithauer B . Primary epithelioid hemangioendothelioma of the brain. Am J Surg Pathol. 1996; 20(6):707-14. DOI: 10.1097/00000478-199606000-00008. View

13.

Nayler S, Rubin B, Calonje E, Chan J, Fletcher C . Composite hemangioendothelioma: a complex, low-grade vascular lesion mimicking angiosarcoma. Am J Surg Pathol. 2000; 24(3):352-61. DOI: 10.1097/00000478-200003000-00003. View

14.

Zhang J, Wu B, Zhou G, Zhang R, Wei X, Yu B . Composite hemangioendothelioma arising from the kidney: case report with review of the literature. Int J Clin Exp Pathol. 2013; 6(9):1935-41. PMC: 3759503. View

15.

Venizelos I, Paradinas F . Primary paediatric intracranial epithelioid haemangioendothelioma. Histopathology. 2002; 41(2):172-4. DOI: 10.1046/j.1365-2559.2002.01424_3.x. View

16.

Chow L, Chow W, Fong D . Epithelioid hemangioendothelioma of the brain. Am J Surg Pathol. 1992; 16(6):619-25. DOI: 10.1097/00000478-199206000-00010. View

17.

Das S, Deora H, Rao S, Kandregula S, Narayana S . Intracranial kaposiform hemangioendothelioma presenting as epistaxis: a rare case report with review of literature. Childs Nerv Syst. 2020; 37(6):2057-2062. DOI: 10.1007/s00381-020-04905-y. View

18.

Batista K, Gomez G, Murias Quintana E, Astudillo A, Fernandez-Vega I, Alvarez Fernandez B . Giant cranionasal epithelioid haemangioendothelioma with invasive growth pattern mimicking a skull base chondrosarcoma. Contemp Oncol (Pozn). 2018; 22(2):118-123. PMC: 6103236. DOI: 10.5114/wo.2018.76235. View

19.

Bhat A, Chowdappa V . Composite Hemangioendothelioma: Report of a Rare Case. J Clin Diagn Res. 2016; 10(10):ED01-ED03. PMC: 5121686. DOI: 10.7860/JCDR/2016/19994.8602. View

20.

Yoda Y, Ohashi M . A case of composite hemangioendothelioma arising from the spleen. Jpn J Clin Oncol. 2012; 42(8):770. DOI: 10.1093/jjco/hys118. View