Sleep Duration and Lipid Metabolism in Patients with Diabetes Mellitus: from the POWER2DM Study

Overview

Journal Sleep Biol Rhythms

Date 2024 Mar 12

PMID 38468620

Authors

Isabel Perez-Corral

Francisco Gomez-Delgado

Merel M Ruissen

Jose D Torres-Pena

Antonio P Arenas-de Larriva

Jacob K Sont

Albert A de Graaf

Bas S Uitbeijerse

Eelco J P de Koning

Javier Delgado-Lista

Affiliations

Soon will be listed here.

Abstract

This study assesses the association between sleep duration and plasma lipid profiles in people with diabetes mellitus (DM). Sleep duration data were obtained in 91 patients from the POWER2DM study (NCT03588104). The patients were divided in tertiles, based on their sleep duration, and blood samples were obtained at the beginning and after 9 months. Significant differences were found, specifically, patients in Tertile 3 (≥ 7.51 h) showed lower plasma levels of high-density lipoprotein cholesterol HDL-c ( < 0.05), apolipoprotein A1 (apo-A1; < 0.05) and low HDL-c/apo-A1 ratio ( < 0.05). This study shows that sleep duration is associated with plasma lipid profiles in people with DM.

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