Obstructive Sleep Apnea: The Effect of Bariatric Surgery After Five Years-A Prospective Multicenter Trial

Overview

Journal Obes Surg

Date 2024 Mar 8

PMID 38457003

Authors

Pipsa Peromaa-Haavisto

Markku Luostarinen

Risto Juusela

Henri Tuomilehto

Jyrki Kossi

Affiliations

Soon will be listed here.

Abstract

Background: The prevalence of obstructive sleep apnea (OSA) is high among the bariatric surgery candidates. Obesity is the most important individual risk factor for OSA. The aim of this study was to investigate the effect of a laparoscopic Roux-en-Y gastric bypass (LRYGB) on OSA 5 years after the surgery.

Patients And Methods: In this prospective multicenter study, standard overnight cardiorespiratory recording was conducted to 150 patients at baseline prior to bariatric surgery. A total of 111 (73.3%) patients of those had OSA. Cardiorespiratory recordings at 5 years after surgery were available for 70 OSA patients. The changes in anthropometric and demographic measurements including age, weight, body mass index (BMI), and waist and neck circumference were evaluated. Also, a quality of life (QoL) questionnaire 15D administered in a baseline was controlled at 5-year follow-up visit.

Results: At 5-year OSA was cured in 55% of patients, but moderate or severe OSA still persisted in 20% of patients after operation. Mean total AHI decreased from 27.8 events/h to 8.8 events/h (p < 0.001) at 5-year follow-up. A clinically significant difference in QoL was seen in mobility, breathing, sleeping, usual activities, discomfort and symptoms, vitality and sexual activity. The QoL total score improved more in OSA patient at 5-year follow-up.

Conclusions: LRYGB is an effective treatment of OSA in obese patients and the achieved beneficial outcomes are maintained at 5-year follow-up.

Citing Articles

Treatment of OSA and its Impact on Cardiovascular Disease, Part 2: JACC State-of-the-Art Review.

Javaheri S, Javaheri S, Gozal D, Campos-Rodriguez F, Martinez-Garcia M, Mokhlesi B J Am Coll Cardiol. 2024; 84(13):1224-1240.

PMID: 39293885 PMC: 11668537. DOI: 10.1016/j.jacc.2024.07.024.

Sleep Quality and Bariatric Surgery-Can We Treat Sleep Disturbances and Insomnia in Patients with Obesity with Laparoscopic Sleeve Gastrectomy?.

Wyszomirski K, Slubowska A, Debski J, Skibiak K, Przybylowski J, Czerwinska M J Clin Med. 2024; 13(16).

PMID: 39200961 PMC: 11355848. DOI: 10.3390/jcm13164820.

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