Risk Factors of Perinatal Negative Mood and Its Influence on Prognosis: A Retrospective Cohort Study

Overview

Journal Psychol Res Behav Manag

Publisher Dove Medical Press

Specialty Social Sciences

Date 2024 Mar 6

PMID 38444720

Authors

Zheng Yang

Cuixiang Shao

Chen Tang

Affiliations

Soon will be listed here.

Abstract

Background: Maternal anxiety or depression in the perinatal period has a high prevalence. The negative emotion during the puerpera is unfavorable to the process of childbirth and also affects the recovery and the quality of life in postpartum patients significantly. The present study aimed to elucidate the risk factors of negative emotion in perinatal women and its influence on prognosis to provide a reference for improving maternal prognosis.

Methods: Initially, 350 expectant mothers were randomly enrolled in the present study between August 2021 and August 2022. Among these, after applying the established inclusion and exclusion criteria, 314 patients were eventually selected. The independent risk factors of negative emotion and poor prognosis were analyzed through binary logistics regression and multiple linear regression. Follow-up was conducted via telephone, email, and a follow-up visit one month after discharge.

Results: Among the included patients, 18 (5.7%) had prenatal anxiety, 16 (5.1%) had prenatal depression, 31 (9.9%) had postnatal anxiety, and 28 (8.9%) had postnatal depression. Perinatal negative emotional risk factors include age, marital relationship, regular prenatal examination, E2 level, 5-HT level before and after delivery, family monthly income, neonatal health, breastfeeding time, intrapartum hemorrhage, constipation and other complications. The development of postpartum negative emotions is a risk factor for maternal prognosis.

Conclusion: The results showed that the risk factors of perinatal depression and anxiety were complex. In order to improve the quality of life of pregnant women, maintain their long-term emotional stability, and promote their postpartum recovery, it may be considered to promote the use of screening tools to identify women at risk of anxiety and depression before and after delivery, and timely psychological counseling for patients with high risk factors to promote their mental health.

References

Nair A, Manchanda S, Gamanagatti S, Kachhawa G, Bhatla N . Post caesarean section complications conundrum: Role of imaging. Br J Radiol. 2022; 95(1138):20211344. PMC: 9815736. DOI: 10.1259/bjr.20211344. View

van der Zee-van den Berg A, Boere-Boonekamp M, Groothuis-Oudshoorn C, Reijneveld S . Postpartum depression and anxiety: a community-based study on risk factors before, during and after pregnancy. J Affect Disord. 2021; 286:158-165. DOI: 10.1016/j.jad.2021.02.062. View

Dagher R, Bruckheim H, Colpe L, Edwards E, White D . Perinatal Depression: Challenges and Opportunities. J Womens Health (Larchmt). 2020; 30(2):154-159. PMC: 7891219. DOI: 10.1089/jwh.2020.8862. View

Saxbe D, Dunkel Schetter C, Guardino C, Ramey S, Shalowitz M, Thorp J . Sleep Quality Predicts Persistence of Parental Postpartum Depressive Symptoms and Transmission of Depressive Symptoms from Mothers to Fathers. Ann Behav Med. 2016; 50(6):862-875. PMC: 6644068. DOI: 10.1007/s12160-016-9815-7. View

Misri S, Swift E . Generalized Anxiety Disorder and Major Depressive Disorder in Pregnant and Postpartum Women: Maternal Quality of Life and Treatment Outcomes. J Obstet Gynaecol Can. 2015; 37(9):798-803. DOI: 10.1016/S1701-2163(15)30150-X. View

Sorrentino F, Greco F, Palieri T, Vasciaveo L, Stabile G, Carlucci S . Caesarean Section on Maternal Request-Ethical and Juridic Issues: A Narrative Review. Medicina (Kaunas). 2022; 58(9). PMC: 9506057. DOI: 10.3390/medicina58091255. View

Patton G, Romaniuk H, Spry E, Coffey C, Olsson C, Doyle L . Prediction of perinatal depression from adolescence and before conception (VIHCS): 20-year prospective cohort study. Lancet. 2015; 386(9996):875-83. DOI: 10.1016/S0140-6736(14)62248-0. View

De Bortoli J, Amir L . Is onset of lactation delayed in women with diabetes in pregnancy? A systematic review. Diabet Med. 2015; 33(1):17-24. DOI: 10.1111/dme.12846. View

Biaggi A, Conroy S, Pawlby S, Pariante C . Identifying the women at risk of antenatal anxiety and depression: A systematic review. J Affect Disord. 2015; 191:62-77. PMC: 4879174. DOI: 10.1016/j.jad.2015.11.014. View

10.

McLeod G, Sherriff J, Hartmann P, Nathan E, Geddes D, Simmer K . Comparing different methods of human breast milk fortification using measured v. assumed macronutrient composition to target reference growth: a randomised controlled trial. Br J Nutr. 2015; 115(3):431-9. DOI: 10.1017/S0007114515004614. View

11.

Gavin N, Gaynes B, Lohr K, Meltzer-Brody S, Gartlehner G, Swinson T . Perinatal depression: a systematic review of prevalence and incidence. Obstet Gynecol. 2005; 106(5 Pt 1):1071-83. DOI: 10.1097/01.AOG.0000183597.31630.db. View

12.

Rana M, Jain S, Choubey P . Prolactin and its significance in the placenta. Hormones (Athens). 2022; 21(2):209-219. DOI: 10.1007/s42000-022-00373-y. View

13.

Garay S, Savory K, Sumption L, Penketh R, Jones I, Janssen A . Seasonal variation in salivary cortisol but not symptoms of depression and trait anxiety in pregnant women undergoing an elective caesarean section. Psychoneuroendocrinology. 2019; 108:14-19. PMC: 6854466. DOI: 10.1016/j.psyneuen.2019.05.029. View

14.

Norhayati M, Nik Hazlina N, Asrenee A, Emilin W . Magnitude and risk factors for postpartum symptoms: a literature review. J Affect Disord. 2015; 175:34-52. DOI: 10.1016/j.jad.2014.12.041. View

15.

Popova N, Tsybko A, Naumenko V . The Implication of 5-HT Receptor Family Members in Aggression, Depression and Suicide: Similarity and Difference. Int J Mol Sci. 2022; 23(15). PMC: 9369404. DOI: 10.3390/ijms23158814. View

16.

Bridwell M, Handzel E, Hynes M, Jean-Louis R, Fitter D, Hogue C . Hypertensive disorders in pregnancy and maternal and neonatal outcomes in Haiti: the importance of surveillance and data collection. BMC Pregnancy Childbirth. 2019; 19(1):208. PMC: 6585002. DOI: 10.1186/s12884-019-2361-0. View

17.

Blair C, Granger D, Willoughby M, Kivlighan K . Maternal sensitivity is related to hypothalamic-pituitary-adrenal axis stress reactivity and regulation in response to emotion challenge in 6-month-old infants. Ann N Y Acad Sci. 2007; 1094:263-7. DOI: 10.1196/annals.1376.031. View

18.

Gelaye B, Rondon M, Araya R, Williams M . Epidemiology of maternal depression, risk factors, and child outcomes in low-income and middle-income countries. Lancet Psychiatry. 2016; 3(10):973-982. PMC: 5155709. DOI: 10.1016/S2215-0366(16)30284-X. View

19.

Liu X, Wang S, Wang G . Prevalence and Risk Factors of Postpartum Depression in Women: A Systematic Review and Meta-analysis. J Clin Nurs. 2021; 31(19-20):2665-2677. DOI: 10.1111/jocn.16121. View

20.

Okun M, Mancuso R, Hobel C, Dunkel Schetter C, Coussons-Read M . Poor sleep quality increases symptoms of depression and anxiety in postpartum women. J Behav Med. 2018; 41(5):703-710. PMC: 6192841. DOI: 10.1007/s10865-018-9950-7. View