Emergence and Spread of at Different Geographic Scales

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2024 Mar 5

PMID 38441471

Authors

Martial Briand

Alexandra Boccarossa

Adrien Rieux

Marie-Agnes Jacques

Line Ganlanon

Christian Johnson

Matthieu Eveillard

Laurent Marsollier

Estelle Marion

Affiliations

Soon will be listed here.

Abstract

Importance: is an environmental mycobacterial pathogen that can cause Buruli ulcer, a severe cutaneous infection, mostly spread in Africa and Australia. We conducted a large genomic study of , combining genomic and evolutionary approaches to decipher its evolutionary history and pattern of spread at different geographic scales. At the scale of villages in an endemic area of Benin, the circulating genotypes have been introduced in recent decades and are not randomly distributed along the river. On a global scale, has been spreading for much longer, resulting in distinct and compartmentalized endemic foci across Africa and Australia.

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