is a Potential Marker of Altered Gut Microbiota in Psoriasis and Psoriatic Arthritis

Overview

Journal Microbiol Spectr

Specialty Microbiology

Date 2024 Mar 5

PMID 38441468

Authors

Yue Xiao

Yiyi Wang

Bangzhuo Tong

Yuanxia Gu

Xingli Zhou

Ning Zhu

Xiaomin Xu

Xiaochen Yin

Yan Kou

Yan Tan

Jincheng Wang

Wei Li

Affiliations

Soon will be listed here.

Abstract

Importance: In this observational clinical study with sufficient sample size and metagenomic sequencing to profile the gut microbiota, we identified consistent signals of the depleted abundance of and related functional genes among psoriatic patients, including those with psoriatic arthritis. may serve as an ecologically important functional unit in the gut microbiota, holding potential as a diagnostic marker and target for therapeutic interventions to achieve lasting effects. Our findings provide comprehensive gut microbiota profiling in psoriasis, resolving previous contradictions and generating new hypotheses for further investigation. These insights may significantly impact psoriasis management and related conditions.

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