Sleep Disorders, Sleep Medication Use, and Predictors of Sleep Disturbance in Children with Persistent Tic Disorders

Overview

Journal Child Health Care

Specialty Health Services

Date 2024 Mar 4

PMID 38435344

Authors

Valerie Swisher

Maya Tooker

Christine Qu

Helen J Burgess

Meredith E Coles

Shannon Bennett

John Piacentini

Christopher S Colwell

Emily J Ricketts

Affiliations

Soon will be listed here.

Abstract

The present study examined rates of sleep disorders and sleep medication use, and predictors of sleep disturbance in children with persistent tic disorders (PTD). Sixty-three parents of children aged 10 to 17 years with PTDs completed an internet survey evaluating sleep patterns and clinical symptoms. Insomnia (19.4%), nightmares (16.1%), and bruxism (13.1%) were the most commonly reported lifetime sleep disorders. Fifty-two percent endorsed current sleep medication use. Higher ADHD severity, overall life impairment, and female sex predicted greater sleep disturbance. Findings suggest the utility of clinical management of co-occurring ADHD and impairment to mitigate sleep disturbance in children with PTDs.

References

Lunsford-Avery J, Krystal A, Kollins S . Sleep disturbances in adolescents with ADHD: A systematic review and framework for future research. Clin Psychol Rev. 2016; 50:159-174. PMC: 5401800. DOI: 10.1016/j.cpr.2016.10.004. View

Conelea C, Woods D, Zinner S, Budman C, Murphy T, Scahill L . The impact of Tourette Syndrome in adults: results from the Tourette Syndrome impact survey. Community Ment Health J. 2011; 49(1):110-20. DOI: 10.1007/s10597-011-9465-y. View

Lewin A, Storch E, Conelea C, Woods D, Zinner S, Budman C . The roles of anxiety and depression in connecting tic severity and functional impairment. J Anxiety Disord. 2010; 25(2):164-8. DOI: 10.1016/j.janxdis.2010.08.016. View

McGuire J, Arnold E, Park J, Nadeau J, Lewin A, Murphy T . Living with tics: reduced impairment and improved quality of life for youth with chronic tic disorders. Psychiatry Res. 2014; 225(3):571-9. PMC: 4314444. DOI: 10.1016/j.psychres.2014.11.045. View

Rombach I, Gray A, Jenkinson C, Murray D, Rivero-Arias O . Multiple imputation for patient reported outcome measures in randomised controlled trials: advantages and disadvantages of imputing at the item, subscale or composite score level. BMC Med Res Methodol. 2018; 18(1):87. PMC: 6114240. DOI: 10.1186/s12874-018-0542-6. View

Austin P, Steyerberg E . The number of subjects per variable required in linear regression analyses. J Clin Epidemiol. 2015; 68(6):627-36. DOI: 10.1016/j.jclinepi.2014.12.014. View

Garris J, Quigg M . The female Tourette patient: Sex differences in Tourette Disorder. Neurosci Biobehav Rev. 2021; 129:261-268. DOI: 10.1016/j.neubiorev.2021.08.001. View

Chase R, Pincus D . Sleep-related problems in children and adolescents with anxiety disorders. Behav Sleep Med. 2011; 9(4):224-36. DOI: 10.1080/15402002.2011.606768. View

Hibberd C, Charman T, Bhatoa R, Tekes S, Hedderly T, Gringras P . Sleep difficulties in children with Tourette syndrome and chronic tic disorders: a systematic review of characteristics and associated factors. Sleep. 2019; 43(6). DOI: 10.1093/sleep/zsz308. View

10.

Bloch M, Leckman J . Clinical course of Tourette syndrome. J Psychosom Res. 2009; 67(6):497-501. PMC: 3974606. DOI: 10.1016/j.jpsychores.2009.09.002. View

11.

Alvaro P, Roberts R, Harris J, Bruni O . The direction of the relationship between symptoms of insomnia and psychiatric disorders in adolescents. J Affect Disord. 2016; 207:167-174. DOI: 10.1016/j.jad.2016.08.032. View

12.

Mitchell M, Gehrman P, Perlis M, Umscheid C . Comparative effectiveness of cognitive behavioral therapy for insomnia: a systematic review. BMC Fam Pract. 2012; 13:40. PMC: 3481424. DOI: 10.1186/1471-2296-13-40. View

13.

Riviere J, Xiong L, Levchenko A, St-Onge J, Gaspar C, Dion Y . Association of intronic variants of the BTBD9 gene with Tourette syndrome. Arch Neurol. 2009; 66(10):1267-72. DOI: 10.1001/archneurol.2009.213. View

14.

Ricketts E, Rozenman M, Choy C, Goldberg H, Kim J, Colwell C . Sleep Sufficiency in Pediatric and Adolescent Tourette's Disorder: National Survey of Children's Health. J Dev Behav Pediatr. 2017; 39(1):72-76. PMC: 5747545. DOI: 10.1097/DBP.0000000000000518. View

15.

Smith B, Ludlow A . Patterns of Nutritional Supplement Use in Children with Tourette Syndrome. J Diet Suppl. 2021; 20(1):28-43. DOI: 10.1080/19390211.2021.1958120. View

16.

Sambrani T, Jakubovski E, Muller-Vahl K . New Insights into Clinical Characteristics of Gilles de la Tourette Syndrome: Findings in 1032 Patients from a Single German Center. Front Neurosci. 2016; 10:415. PMC: 5018493. DOI: 10.3389/fnins.2016.00415. View

17.

Storch E, Murphy T, Lack C, Geffken G, Jacob M, Goodman W . Sleep-related problems in pediatric obsessive-compulsive disorder. J Anxiety Disord. 2007; 22(5):877-85. PMC: 2413417. DOI: 10.1016/j.janxdis.2007.09.003. View

18.

Ghanizadeh A, Mosallaei S . Psychiatric disorders and behavioral problems in children and adolescents with Tourette syndrome. Brain Dev. 2008; 31(1):15-9. DOI: 10.1016/j.braindev.2008.03.010. View

19.

Lebowitz E, Motlagh M, Katsovich L, King R, Lombroso P, Grantz H . Tourette syndrome in youth with and without obsessive compulsive disorder and attention deficit hyperactivity disorder. Eur Child Adolesc Psychiatry. 2012; 21(8):451-7. PMC: 3722559. DOI: 10.1007/s00787-012-0278-5. View

20.

Owens J, Spirito A, McGuinn M . The Children's Sleep Habits Questionnaire (CSHQ): psychometric properties of a survey instrument for school-aged children. Sleep. 2001; 23(8):1043-51. View