Endoscopic Findings of 'Salmon Roe-like Nodular Lesions' in a Case of Severe Disseminated Strongyloidiasis in a Foreign Resident in Japan

Overview

Journal Intern Med

Specialty General Medicine

Date 2024 Mar 3

PMID 38432976

Authors

Keigo Kobayashi

Yasuhiro Umekawa

Affiliations

Soon will be listed here.

Abstract

A Southeast Asian man in his 30s residing in Japan developed severe disseminated strongyloidiasis during long-term steroid therapy. Initially misdiagnosed as gastroenteritis, his condition was later identified as strongyloidiasis by fecal smears and endoscopy. An endoscopic examination revealed salmon roe-like nodular lesions, indicating an advanced stage. Despite treatment, the patient died of the illness. This case underscores the importance of considering the patient's geographical background and immunosuppressive history in medical assessments. It further highlights the need for early and proactive diagnostic approaches, such as stool testing and gastrointestinal endoscopy, to effectively detect and treat imported infectious diseases.

References

Williams J, Nunley D, Dralle W, Berk S, Verghese A . Diagnosis of pulmonary strongyloidiasis by bronchoalveolar lavage. Chest. 1988; 94(3):643-4. DOI: 10.1378/chest.94.3.643. View

Ikuno H, Ishikawa T, Norose K . Status of Strongyloidiasis in Japan, 2000-2017. Am J Trop Med Hyg. 2020; 103(2):727-734. PMC: 7410411. DOI: 10.4269/ajtmh.19-0969. View

Smith B, Verghese A, Guiterrez C, Dralle W, Berk S . Pulmonary strongyloidiasis. Diagnosis by sputum gram stain. Am J Med. 1985; 79(5):663-6. DOI: 10.1016/0002-9343(85)90068-3. View

Keiser P, Nutman T . Strongyloides stercoralis in the Immunocompromised Population. Clin Microbiol Rev. 2004; 17(1):208-17. PMC: 321465. DOI: 10.1128/CMR.17.1.208-217.2004. View

Buonfrate D, Perandin F, Formenti F, Bisoffi Z . A retrospective study comparing agar plate culture, indirect immunofluorescence and real-time PCR for the diagnosis of Strongyloides stercoralis infection. Parasitology. 2017; 144(6):812-816. DOI: 10.1017/S0031182016002559. View

Buonfrate D, Requena-Mendez A, Angheben A, Munoz J, Gobbi F, van den Ende J . Severe strongyloidiasis: a systematic review of case reports. BMC Infect Dis. 2013; 13:78. PMC: 3598958. DOI: 10.1186/1471-2334-13-78. View

Lam C, Tong M, Chan K, Siu Y . Disseminated strongyloidiasis: a retrospective study of clinical course and outcome. Eur J Clin Microbiol Infect Dis. 2006; 25(1):14-8. DOI: 10.1007/s10096-005-0070-2. View

Hirata T, Nakamura H, Kinjo N, Hokama A, Kinjo F, Yamane N . Increased detection rate of Strongyloides stercoralis by repeated stool examinations using the agar plate culture method. Am J Trop Med Hyg. 2007; 77(4):683-4. View

Thompson B, Fry L, Wells C, Olmos M, Lee D, Lazenby A . The spectrum of GI strongyloidiasis: an endoscopic-pathologic study. Gastrointest Endosc. 2004; 59(7):906-10. DOI: 10.1016/s0016-5107(04)00337-2. View

10.

Suzuki J, Hasekura S, Imai H, Endo S . Chlamydia Proctitis. Intern Med. 2023; 63(8):1179. PMC: 11081884. DOI: 10.2169/internalmedicine.2396-23. View

11.

Olsen A, van Lieshout L, Marti H, Polderman T, Polman K, Steinmann P . Strongyloidiasis--the most neglected of the neglected tropical diseases?. Trans R Soc Trop Med Hyg. 2009; 103(10):967-72. DOI: 10.1016/j.trstmh.2009.02.013. View

12.

Ly M, Bethel S, Usmani A, Lambert D . Cutaneous Strongyloides stercoralis infection: an unusual presentation. J Am Acad Dermatol. 2003; 49(2 Suppl Case Reports):S157-60. DOI: 10.1067/mjd.2003.338. View