» Articles » PMID: 38413624

Association of Adverse Childhood Experiences with Anemia in Older Chinese: Guangzhou Biobank Cohort Study

Overview
Journal Sci Rep
Specialty Science
Date 2024 Feb 27
PMID 38413624
Authors
Affiliations
Soon will be listed here.
Abstract

To examine the association of adverse childhood experiences (ACEs) with anemia among older people. 24,116 participants aged 50 years or above were recruited. Multivariable linear and logistic regression was used to assess the associations of self-reported ACEs number with hemoglobin concentrations (g/dL) and presence of anemia. Older individuals with two or more ACEs, versus no ACEs, showed lower hemoglobin concentrations (β =  - 0.08 g/dL, 95% confidence intervals (CI) - 0.12 to - 0.03) and higher odds of anemia (odds ratio = 1.26, 95% CI 1.01-1.59). A more pronounced association between ACEs and anemia in the lower education group was found, while the association became non-significant in those with higher education (P for ACEs-education interaction = 0.02). ACEs was associated with anemia in older people, and the association was stronger in those with lower education, highlighting the significance of early-life psychological stressors assessment and consideration of education background in geriatric care.

References
1.
Ozieh M, Garacci E, Campbell J, Walker R, Egede L . Adverse Childhood Experiences and Decreased Renal Function: Impact on All-Cause Mortality in U.S. Adults. Am J Prev Med. 2020; 59(2):e49-e57. PMC: 7378887. DOI: 10.1016/j.amepre.2020.04.005. View

2.
Li L, Rao K, Kong L, Yao C, Xiang H, Zhai F . [A description on the Chinese national nutrition and health survey in 2002]. Zhonghua Liu Xing Bing Xue Za Zhi. 2005; 26(7):478-84. View

3.
Chen Y, Xu S, Xu Y, Li W, Chen K, Cai J . Inflammatory anemia may be an indicator for predicting disease activity and structural damage in Chinese patients with rheumatoid arthritis. Clin Rheumatol. 2020; 39(6):1737-1745. DOI: 10.1007/s10067-019-04873-y. View

4.
Wei C, Zhou J, Huang X, Li M . Effects of psychological stress on serum iron and erythropoiesis. Int J Hematol. 2008; 88(1):52-56. DOI: 10.1007/s12185-008-0105-4. View

5.
Dhabhar F . Effects of stress on immune function: the good, the bad, and the beautiful. Immunol Res. 2014; 58(2-3):193-210. DOI: 10.1007/s12026-014-8517-0. View