The Mycoplasmacidal Properties of Sodium Hypochlorite
Overview
Affiliations
The effect of hypochlorite concentration on Mycoplasma mycoides ssp. mycoides viability was tested under a variety of conditions. The experimental variables employed included chlorine-cell contact time, chlorine concentration, carrier system and organic loading. Initial populations of 10(6) c.f.u./ml were killed (no survivors in 1 ml) by hypochlorite solution containing 25 p.p.m. available chlorine in 15 s in the absence of organic load and 50 p.p.m. available chlorine in 5 min in the presence of 1% protein. Higher concentrations of hypochlorite were required to disinfect a porous carrier system in the absence or presence of protein. The results are in contrast to previous reports that M. bovis is killed only by high hypochlorite concentrations.
Chemical disinfectants in ophthalmic practice.
Parikh S, Parikh R Indian J Ophthalmol. 2021; 69(3):510-516.
PMID: 33595464 PMC: 7942131. DOI: 10.4103/ijo.IJO_1549_20.
Lee D, Miles R, Inal J Epidemiol Infect. 1987; 98(3):361-8.
PMID: 3297746 PMC: 2235357. DOI: 10.1017/s0950268800062129.